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Question 1

Pharmacokinetics

Answer 1

Pharmacokinetics describes the effects of the body on drugs (absorption, distribution, excretion)

Question 2

pharmacodynamics

Answer 2

pharmacodynamics describes the action of drugs on the body such as the mechanism of action and therapeutic and toxic effects.

Question 3

Fick’s law of diffusion

Answer 3

Rate = (C1-C2) x (Permeability coefficient x Area)/

Thickness

Question 4

pharmacodynamic tolerance

Answer 4

down-regulation or desensitization- a reduction in the number of receptors

Question 5

pharmacodynamic sensitization

Answer 5

Up-regulation- increase in the number of receptors

Question 6

COMPETITIVE ANTAGONISM

Answer 6

Reversible competition for agonist receptor binding sites without inducing a biological response. (Blocks binding)

Question 7

NON-COMPETITIVE ANTAGONISM

Answer 7

Irreversible binding with receptor preventing agonist binding to receptor