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Antibiotics > 1 > Flashcards

1 Flashcards

1
Q

aminoglycoside coverage (general)

A

Gentamicin synergistically with beta lactams or vanco for gram positive; staph and enterococcus. Mainly gram negative; pseudomonas. Monotherapy uncommon.

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2
Q

aminoglycoside with: broadest spectrum of activity

A

amikacin

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3
Q

T/F: AGS have anaerobes in their spectrum

A

false

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4
Q

T/F: penicillins have atypicals in their spectrum

A

false

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5
Q

penicillins with: activity against enterococci (gram positive short chain)

A

ampicillin, amoxicillin, piperacillin

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6
Q

penicillins with: activity against MSSA

A

nafcillin, oxacillin

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7
Q

penicillins with: improved gram negative coverage

A

piperacillin (ticarcillin but nobody uses it)

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8
Q

penicillins with: pseudomonal coverage

A

piperacillin

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9
Q

penicillins coverage (general)

A

Mainly gram positive cocci. Some gram negative rods.

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10
Q

penicillins with: anaerobic coverage

A

amox+clav, pip+tazo, amp+sulbac

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11
Q

T/F: Penicillins can be used to treat bacteriodes, haemophilius, and neisseria

A

True if combined with clavulanate, sulbactam, or tazobactam

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12
Q

DOC penicillin for: IE, AOM, h.pylori

A

amoxicillin

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13
Q

T/F: early generation cephalosporins have improved best gram negative coverage

A

false. early=better gram positive

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14
Q

cephalosporins coverage (general)

A

tricked ya depends on generations mostly

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15
Q

cephalosporin generation with: HNPEK coverage

A

2nd generation

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16
Q

cephalosporin generation with: PEK coverage

A

1st generations

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17
Q

cephalosporin generation with: HNPEKS coverage

A

3rd generation

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18
Q

cephalosporin generation with: HNPEKS and CAPES coverage

A

4th generation

19
Q

bacteria covered in: PEK regimen

A

*proteus mirabilis, e.coli, klebsiella.

[*oxidase-negative]

20
Q

bacteria covered in: HNPEKS regimen

A

PEK+ *haemophilus, *neisseria, serratia

[*fastidious; ox-negative]

21
Q

bacteria covered in: CAPES regimen

A

citrobacter, enterobacter, pseudomonas, acintobacter, serratia [GNR of all categories except fastidious]

22
Q

notable ceftazidime coverage

A

improved gram negative including pseudomonas. less gram positive.

23
Q

cephalosporin generation with: best gram positive coverage

A

5th generation; ceftaroline

24
Q

cephalosporin generation with: best gram negative coverage

A

4th generation; cefepime

25
Q

two ceph generations with: ~equal gram positive activity, but varying negative activity

A

3rd & 4th generation

26
Q

cephalosporin generation with: lower staph & higher step activity

A

2nd & 3rd generation

27
Q

cephalosporin generation with: higher staph & lower strep activity

A

1st generation

28
Q

only two cephalosporins with: anaerobic coverage (bacteriodes)

A

ceFOXitin, cefoTETan. Lose some positive coverage.

29
Q

cephalosporin generation with: gram positive activity similar to 3rd generation but improved gram negative

A

4th generation; cefepime

30
Q

cephalosporin generation with: MRSA but no pseudomonas coverage

A

5th generation; ceftaroline

31
Q

cephalosporins with: pseudomonas coverage

A

cefTAZidime, ceFEPime

32
Q

carbapenems coverage (general)

A

very broad: positive, negative, anaerobic.

33
Q

5 notable gaps in carbapenem coverage

A

atypicals, MRSA, VRE, c. diff, stentotrophomonas

34
Q

T/F: carbapenems cover includes pseudomonas and acintobacter

A

False, not all! Etrapenem does not

35
Q

carbapenem that is not indicated for HAP, VAP, or lung infections

A

doripenem

36
Q

carbapenem that is given with cilastatin to prevent dihydropeptidase in the normal kidney from breaking it down

A

imipenem

37
Q

FQs coverage (general)

A

extensive activity: positive, negative, and average-to-excellent atypical (except ciprofloxacin)

38
Q

FQs with: pseudomonas & enhanced gram negative coverage

A

ciprofloxacin, levofloxacin

39
Q

FQs with: anaerobic & enhanced gram positive coverage

A

moxifloxacin

40
Q

respiratory fluoroquinolones

A

gemifloxacin, levofloxacin, moxifloxacin

41
Q

FQs with: common mixed infections/IAI monotherapy use

A

moxifloxacin

42
Q

FQs with: enahnced strep. pneumo and & atypical coverage

A

gemifloxacin, levofloxacin, moxifloxacin

43
Q

treating pseudomonas with FQs

A

usually requires combo therapy (beta-lactam typical)

Antibiotics (1 decks)

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