1,2 – Evidence-based Medicine Flashcards

1
Q

Many diseases are self-limiting

A
  • “the fact that your patient gets well does NOT prove that your diagnosis (or treatment) was correct”
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2
Q

In the years after you graduate

A
  • Memory of what you learned will be less
  • New treatments, etc. will be found
    o If a good vet, you will NEED to stay up to date of new developments
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3
Q

What is evidence-based medicine?

A
  • Applying the best and most relevant scientific evidence, integrated with clinical expertise
  • While taking in account each patient and owner’s circumstances
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4
Q

EBVM suggest

A
  • Personal experience may be misleading
  • Randomised studies are required to validate results
  • Predictions based on physiological principles are often WRONG
  • Reading literature requires more than common sense to evaluate
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5
Q

Barriers to the process

A
  • Don’t always have the time and resources
  • Difficult to evaluate VALUE of info
  • May be lacking in some areas
  • Lack of rigorous, large-scale clinical studies in vet med
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6
Q

Limitations of EBVM

A
  • Literature base is smaller than human med
  • Need to put emphasis on poorer sources
  • Lack of evidence!
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7
Q

‘just in time’ info: searching mode

A
  • Diseases/conditions that we see rarely
  • Refer or find info to deal with them
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8
Q

Keeping up to date: appraising mode

A
  • See regularly and want to stay up to date
    o Know how to deal with them on a regular basis
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9
Q

Filtered resources

A
  • Summarize, examine and appraise the evidence of MULTIPLE individual studies
  • Only as good as the individual studies (un-filtered resources) examined and the RIGOR at which the review was conducted
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10
Q

Unfiltered resources

A
  • Original research studies
  • Need to take extra care to appraise the resources to ensure VALID and RELIABLE
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11
Q

5 Developments that have made EBM possible

A
  • Develop of strategies for efficiently tracking down and appraising evidence (Ex. PubMed)
  • Creation of systematic reviews and concise summaries
  • Creation of EB journals of secondary publication
    o Vet Evidence
    o Best Bets for Vets
  • *clinician still needs to decided it the evidence applies to the individual patient
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12
Q

Steps of EBVM

A
  1. Convert info needs to answerable questions
  2. Track down best evidence
  3. Critically appraise
  4. Apply results
  5. Evaluate performance
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13
Q

5 A’s of EBVM

A
  • Ask – defining a clinical question
  • Acquire – find best available evidence
  • Appraise – assess quality of evidence
  • Apply – implementing evidence where appropriate
  • Assess – evaluate impact and changes
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14
Q

3 basic strategies for cases

A
  • Appraising mode
  • Searching mode
  • Replicating mode
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15
Q
  • Appraising mode
A

o Conditions we commonly encounter
o Need to be ‘up to the minute’
o Invest time into step 2 and 3

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16
Q
  • Searching mode
A

o Conditions we encounter less often
o Seek out critical appraisals already performed by others
o Step 3 omitted
o Step 2 restricted to sources that have already been critically appraised

17
Q
  • Replicating mode
A

o Blindly seek, accept and apply recommendations

18
Q

Two types of questions

A
  • Background questions
    o General knowledge about a disorder
    o 5 W’s
  • Foreground questions
    o Specific knowledge about managing patients
  • *increase foreground questions when you have more experience with the condition
19
Q

‘PICO’ – the anatomy of a good clinical question

A
  • P: patient/population and/or problem being addressed
  • I: intervention/treatment
  • C: comparison intervention or exposure
  • O: clinical outcomes of interest
20
Q

Example PICO

A
  • P: 20,000 high risk beef calves on a large feedlot
  • I: BRSV vaccination
  • C: do nothing
  • O: morbidity or mortality
  • In high risk beef calves, does vaccination with BRSV vaccine at arrival reduce the level of morbidity or mortality in the pen?
21
Q

Solution to not having time

A
  • Critically Appraised Topics (CAT)
    o Banfield Pet Hospital
  • Best Evidence Topic (BET)
    o Best BETS for Vets
22
Q

CAB international: VetMed Resource

A
  • Most comprehensive indexing and abstracting of vet literature
  • Need to use advanced bibliographic search function