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1
Q

Different between micronutrients, macronutrients

A

Our( energy) is provided by 3 classes of nutrients:
carbohydrates, fats & proteins.⚫ The intake of these nutrients is larger than the other dietary nutrients. So, they are called “macronutrients”.
⚫ Nutrients needed in lesser amounts (vitamins &
minerals) are called the “micronutrients”.

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2
Q

……..l estimates of the amounts of nutrients required to prevent
deficiencies & maintain optimal health.

A

Dietary Reference Intakes DRIs

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3
Q

DRIs replace and expand on

A

Recommended Dietary Allowances

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4
Q

DRIs consist of four dietary reference standards for the intake of nutrients needed for specific……….,………….,……….

1,2,3,4

A

age-groups, physiologic states & gender.

1-Estimated Average Requirement (EAR) : The average daily dietary intake level that meets the requirements of
50% of healthy individuals in a particular life stage and gender group.
2-Recommended Dietary Allowance (RDA): The average daily dietary intake level that is sufficient to meet the
requirements of nearly all the individuals (97–98 %), in a life stage
3-Adequate Intake (AI):estimates of nutrient intake by a group of apparently
healthy people that are assumed to be adequate.

4-Tolerable Upper Intake Level (UL):It is the highest average daily nutrient intake level that is likely to pose
no risk of adverse health effects to almost all individuals in the general population.

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5
Q

The energy generated by
metabolism of macronutrients is used for 3 energy-requiring processes:

A
  1. Resting metabolic rate.60%
  2. Thermic effect of food.10%
  3. Physical activity.30%
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6
Q

Acceptable Macronutrient
Distribution Ranges In Adults:
is ……………… of their
total calories from CHO, ……………… from fat,
and ……………… from protein.

A

is 45%–65% of their
total calories from CHO, 20%–35% from fat,
and 10%–35% from protein.

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7
Q

Dietary fats most strongly influence the incidence of

A

coronary
heart disease (CHD).

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8
Q

Research now indicates that the …….. of fat is more
important than the ………… of fat consumed.

A

type, total amount

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9
Q

The risk for CHD ↑ progressively with ….. levels of serum total cholesterol. A stronger correlation exists between the levels of blood LDLc and CHD, so it is called ……. cholestrol.
• In contrast, ↑ levels of HDLc is associated with a …. risk for CHD.so it is called ………… .

A

↑ bad
↓ good cholesterol

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10
Q

the most important class of dietary
fats.

A

Triacylglycerols

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11
Q

The influence of TAG on blood lipids is determined by the
chemical nature of their constituent fatty acids:

A
  1. The presence or absence of double bonds (saturated vs
    mono- & polyunsaturated),
  2. The number & location of the double bonds.
  3. The trans configuration of the unsaturated fatty acids.
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12
Q

Saturated fatty acids with carbon chain lengths of 14 (……… acid) and 16 (………… acid) are most potent in increasing serum cholesterol.

…………. acid (18 carbons that is found in many foods including
chocolate) produces only modest increases in blood cholesterol.

A

myristic, palmitic

Stearic

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13
Q

Consumption of …………. fats is strongly associated with high levels of total plasma cholesterol and
LDLc, and an increased risk of CHD.

A

Saturated Fats

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14
Q

Monounsaturated Fats: Unsaturated fatty acids, (FAs) are
generally derived from

A

vegetables & fish.

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15
Q

example of a diet rich in monoun- saturated
FAs [MUSFAs], (from olive oil) and ω-3 FAs (from fish
oils & some nuts), but low in saturated fat.

A

Mediterranean Diet

associated with ↓ serum total cholesterol &
LDLc but little change in HDLc

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16
Q

Polyunsaturated Fats
Examples

A

ω-6 Fatty Acids (ω-6 FAs): linoleic acid and linolenic acids. Nuts, avocados, olives, soybeans,
and various oils, including sesame, cottonseed &
corn oil.

ω-3 Fatty Acids: in plants (mainly α-linolenic acid), and in fish oil.

17
Q

EFFECTS of ω-6 FAs:

A

Plasma LDLc are lowered.
▪ But, HDLc, are also lowered, which protect against
CHD.

18
Q

Effect of dietary ω-3 polyunsaturated fats:

A

-Suppress cardiac arrhythmias, -Reduce serum TAG,
-Decrease the tendency for thrombosis,
-Lower blood pressure
reduce risk of cardiovascular mortality.

19
Q

Antithrombotic effects of ω-3 fatty acids:

A

Increased consumption of ω-3 FAs ↓ blood platelet reactivity by inhibiting the conversion of arachidonic acid to thromboxane A2 (TXA2) by the platelets.
• Instead, the ω-3 FAs are converted to TXA3, which is less
thrombogenic than TXA2.

20
Q

In the ……. isomer, hydrogen atoms are on the
same side of the double bond.

• In …… isomer, they are on opposite sites.

A

cis

trans

21
Q

Trans Fatty Acids
▪ They are chemically classified as …………but behave more
likely as ……………..they elevate serum …………..

A

unsaturated FAs

saturated FAs
they elevate serum LDLc (but not
HDLc), so they increase the risk of CHD.

Trans fatty acids do not occur naturally in plants and only occur in small
amounts in animals.

22
Q

Cholesterol is found only in ……… products.

A

animal

consumption should be no more than 300 mg/day.

23
Q

Dietary Factors Affecting CHD:

A

Vitamins B6, B12 & folate

Soy protein: Consumption of 25–50 g/day protein causes
about 10% ↓ in LDLc i

24
Q

The primary role of dietary carbohydrates is to provide

A

energy

25
Q

Monosaccharides:

A

Glucose & fructose

26
Q

Disaccharides

A

sucrose (glucose + fructose), lactose
(glucose + galactose) and maltose (glucose + glucose).
• Sucrose is the ordinary “table sugar,”
• Lactose is the principal sugar found in milk.
• Maltose is a product of enzymatic digestion of poly-saccharides & found
also in significant quantities in malt liquors.

27
Q

Polysaccharides

A

do not have a sweet taste.
▪ Starch found in
abundance in plants. grains, potatoes, dried
peas and beans, and vegetables.

28
Q

Dietary fiber:( as in bran , green leafy vegetables and fruits)

A

non-digestible CHO found in plants
• Provides little energy but has several effects:
• First, it adds bulk to the diet. Fiber can absorb
10–15 times its own weight in water, drawing
fluid into the lumen of the intestine → ↑bowel motility.
• Second, consumption of soluble fiber lowers
LDLc levels.
• Third , give a feeling of satiety.

29
Q

Quality of proteins:

A

Proteins from animal sources: meat, poultry, milk & fish, have a high
quality (contain all essential amino acids).
▪ Proteins from plant sources: wheat, corn & beans have a lower

30
Q

Positive nitrogen balance: nitrogen intake exceeds nitrogen excretion.
oExample,

A

childhood, pregnancy or during recovery from a severe
illness.

31
Q

Negative nitrogen balance: when nitrogen loss is greater than nitrogen

oExample

A

inadequate dietary protein, lack of an
essential amino acid, or during physiologic stresses, such as trauma,
burns, illness, or surgery

32
Q

Protein-Calorie Malnutrition:

A

Kwashiorkor, Marasmus

33
Q

Kwashiorkor occurs when

A

protein deprivation is relatively
greater than the reduction in total calories. , seen in children after weaning their diet consists mainly of carbohydrates.

34
Q

Kwashiorkor Symptoms

A

arrested growth, edema,
skin lesions, depigmented hair, anorexia,
enlarged fatty liver & decreased plasma
albumin concentration.
• Edema may mask muscle loss.Appetit is
poor.

35
Q

Marasmus: occurs when

A

calorie deprivation is relatively greater
than the reduction in protein. occurs in children younger than 1 year

36
Q

Marasmus symptoms

A

Typical symptoms include arrested growth, extreme muscle wasting,
weakness and anemia.Appetit is good.

37
Q

Supplements

A

one exception to this is folic acid. All women of child-bearing age who could become pregnant should take a supplement of 400µg folic first 12 weeks of pregnancy.