07 Anti Infectives

Question 1

Which antibiotics are Cell Wall Inhibitors? (4)

Answer 1

Penicillins, Cephalosporins, Bacitracin, Vancomycin

Question 2

For which type of infections are penicillins predominantly useful

Answer 2

Gram + and anaerobic

Question 3

Which penicillins are PCNase sensitive?

Answer 3

Pen G (IV, IM), and Pen V (PO)

Question 4

Which penicillins are PCNase resistan?

Answer 4

Methacillin, flucloxacillin, dicloxacillin

Question 5

Which drugs are aminopenicillins

Answer 5

ampicillin, amoxicillin

Question 6

Which penicillins have antipseudomonal (Gram -) coverage?

Answer 6

Carboxypenicillins (Carbenicillin and ticarcillin)

Question 7

Which penicillins are carboxypenicillins?

Answer 7

carbenicillin, ticarcillin

Question 8

Which antibiotics are taken on an empty stomach?

Answer 8

penicillin, tetracycline

Question 9

What are topical formulas of Penicillin?

Answer 9

none - allergy risk is too high

Question 10

What hypersensitivity can occur with taking of penicillin?

Answer 10

I anaphylaxis, II hemolytic anemia, III serum sickness, IV SJS

Question 11

Penicillin haptens binding o RBC surface proteins can stimulate what antigenic reactions?

Answer 11

IgE (type I) or IgG (type II)

Question 12

What is the risk of cross reactivity with penicillins?

Answer 12

15% risk with cphalosporins, esp 1st gen