03.04 Abdominal Pain in Infants, Children and Adolescents Flashcards
Step 1 in approach to diagnosis of acute abdominal pain
Establish emergent vs. non-emergent causes of abdominal pain
Sudden or unremitting pain with no prior Hx
Less than 2 weeks
Acute pain
More than 2 weeks
Persistent or current
Chronic
S/sx associated with the cause of an acute abdominal pain
Intestinal inflammation (diarrhea, fever and fatigue, blood in the stool, LOA) Perforation (severe, abdominal distention, fever, nausea and vomiiting) Hemorrhage (weakness, lightheadedness, shortness of breath) Obstruction (bilious vomiting, electrolyte imbalance, borborygmi and ileus) Peritoneal irritation (fever and chills, LOA, abdominal bloating, nausea and vomiting)
Vomiting that precedes a colicky type of abdominal pain suggests problem of _____
AGE
Vomiting that occurs after the onset of pain is suggestive of _______
Surgical condition
Red flag symptoms for surgical consult
Progressive signs of deterioration (restlessness, confusion, weakness, dizziness, tachycardia, hypotension-late sign) Bile-stained or feculent vomitus Involuntary abdominal guarding Rebound abdominal tenderness Marked abdominal distention Signs of acute fluid or blood loss Significant abdominal trauma No obvious etiology
Acute abdominal pain from a GI cause
Appendicitis Malrotation with volvulus Intussusception Intestinal adhesions Strangulated hernia Mesenteric vasculitis Cholelithiasis/cholecystitis Pancreatitis Henoch-Schonlein purpura
Acute abdominal pain from a non-GI cause
Pyelonephritis Renal calculi Ureteropelvic junction obstruction Ovarian torsion or rupture of ovarian cyst Tubo-ovarian abscess Psoas abscess Ectopic pregnancy
Step 2 of the approach to diagnosis of acute abdominal pain
Determine the possible origin of the pain
Most helpful clues in Hx taking for determining the cause of acute abdominal pain
Age (infancy - abdominal colic, 2-5 years - AGE, mesenteric lymphadenitis, acute appendicitis, school age or teenage - Mittelschmerz phenomenon, peptic disease or recurrent intussusception from Meckel’s diverticulum, polyp
Pain history, location, timing, character, duration, radiation
Observation that the further away the pain is from the umbilicus, the greater the likelihood of an organic disease has held up well
Apley’s criteria
Apley’s criteria
Location
Rate on a scale of 1-5, 1-10 or pointing to a series of faces graded from smile to frown
Intensity
Epigastric pain, LUQ
Back radiation
Constant, sharp, boring
Pancreatitis
Periumbilical - lower abdomen
Back radiation
Alternating cramping and painless periods
Intestinal obstruction
Periumbilical, then localized to RLQ
Back or pelvis radiation
Sharp, steady
Appendicitis
Periumbilical to lower abdomen
No radiation
Cramping with painless periods
Intussusception
Back pain (unilateral) Radiation to groin Sharp, intermittent, cramping
Urolithiasis
Back pain, radiating to bladder
Dull to sharp
UTI
Step 3 in the approach to diagnosis of acute abdominal pain
Clinical evaluation
Fever in AGE
Pain follows vomiting
48-72 hours
Rotavirus
Fever in UTI
Painful urination and tenderness in suprapubic area
Triad for diagnosis pneumonia
Fever
Tachypnea
Cough
Abdominal pain in pneumonia
Referred pain
Fever + throat pain + abdominal pain
Acute tonsillopharyngitis
Post-surgery fever + abdominal pain
Intraabdominal abscess
Fever + vomiting + prominent lymph nodes on CT scan
Mesenteric lymphadenitis
Fever + bloody diarrhea + tenesmus + abdominal pain + vomiting
Shigella dysentery
Bilious vomiting, abdominal distention and hypoactive sounds
Intestinal obstruction
Most common causes of vomiting in infancy
Ingestion of mother’s blood in passing out and vomits this when given milk
Gastritis secondary to drugs
Vomiting similar to family members and friends
Diarrhea
Food poisoning
Oral or pharyngeal burns
History of suicidal ideation
Tablets in vomitus
Toxin ingestion
History of NSAID intake
Epigastric tenderness
Blood in vomitus
Gastritis
Peptic ulcer disease
Bilious vomiting + history of abdominal trauma
Duodenal hematoma
Causes splenomegaly
Bleeding from esophageal varices
Portal hypertension
Colickly RUQ pain + fever + vomiting
Acute cholecystitis
Upper abdominal pain + history of drug intake
Erosive gastritis
Upper abdominal pain + tenesmus + severe vomiting
Pancreatitis
Epigastric tenderness + heartburn + eating meals
Peptic ulcer disease
One of the most common functional abdominal diseases showing periumbilical pain
Hx of constipation and soiling
Stool at rectal vault
Palpable sigmoid
Constipation
Periumbilical pain + fever + point tenderness
Acute appendicitis
Hx of chronic abdominal pain
Incongruent signs and symptoms
Normal screening tests
Functional abdominal pain
The most common cause of blood in the stools in infant would be ____
Lower abdomen pain
Anal fissure (treated with lubricant)
Second most common cause of blood in the stools is ____
Lower abdomen pain
AGE
Infectious diarrhea
Third most common cause of blood in the stools
Allergic proctocolitis
Lower abdomen pain
Hx of constipation and soiling
Stool at rectal vault
Palpable sigmoid
Constipation
Lower abdomen pain
Blood in stools
Tenesmus
Fever
Colitis
History of sexual activity
Vaginal discharge
Rectal or vaginal tenderness
Lower abdomen pain
Pelvic inflammatory disease
Dysuria
Hematuria
Suprapubic tenderness
Lower abdomen pain
Cystitis
Diagnostic tests
Hema: CBC, blood smear and ESR
Urinalysis, stool exam
CXR, AXR, Scout film (volvulus), CT scan (appendix - fat stranding), US (to rule out choledochal cyst)
Severe constipation
Abdominal distention
Bilious emesis
Increased bowel sounds
Obstipation
Choledochal cysts triad
Abdominal pain
Jaundice
Abdominal mass
Long-lasting intermittent or constant abdominal pain that is functional or organic
Chronic abdominal pain
A disorder caused by a detectable physiological or structural change in an organ
Organic pain
ABdominal pain without demonstrable evidence of pathologic condition, e.g. anatomic, metabolic, infectious, etc
Functional dyspepsia, irritable bowel syndrome, abdominal migraine
Functional abdominal pain
Includes variable combination of age dependent, chronic or recurrent GI symptoms
Potentially debilitating group of disorders which can affect the quality of life of patient and family
Functional GI disorders
Pain for more than 2 weeks duration and a child must meet a certain criterion
Recurrent abdominal pain
Pain with poor relation to gut function and decreased activities of daily living
Functional abdominal pain
Pain that persists for greater than 6 months without evidence of physiologic events and also interferes with daily functioning
Functional abdominal pain syndrome
Functional dyspepsia, functional abdominal pain
Abdominal migraine
Irritable bowel syndrome
FGIDs
Acute persistent pain increasing in intensity
Sharply localized
Awakens at night
Further away
Fever, anorexia, vomiting, weight loss, anemia, elevated ESR
Organic
Less likely to change Various locations No effect in sleep At umbilicus Headache, dizziness, multiple system complaints With psychological stress
Functional
FGIDs are best understood from a _______
Biophychosocial perspective
Criteria for childhood FGID
Rome III Criteria
FGIDs in neonates and toddlers may present with abdominal pain
Infant colic
Infant dyschezia
Functional constipation
Unclear etiology
Part of the normal distribution of crying
Painful gut contractions, lactose intolerance, gas or parental misinterpretation of normal crying
Infant colic
Infant colic Dx criteria
All in infants 0-4 months of age: paroxysms of irritability, fussing or crying that start and stop with obvious cause, episodes lasting 3 or more hours a day, occurring at least 3 days per week for at least 1 week, no failure to thrive
Clinical evaluation of infant colic
Younger than 4-5 months Crying with temporal features No CNS abnormalities No developmental deficiencies Normal PE Normal growth patterns
Treatment of infant colic
Non-analgesic, non-nutritive soothing maneuvers (rocking, patting)
Self-limiting
Milk intolerance or esophagitis (hyrolyzed protein formula)
Disorder of defecation
Grunting baby syndrome
Infant dyschezia
Infant dyschezia Dx criteria
Both in younger than 6 months: at least 10 minutes of straining and crying before successful passage of stools
No other health problems
Failure to coordinate increased intaabdominal pressure with pelvic floor relaxation
Infant dyschezia
Clinical evaluation of infant dyschezia
Hx
PE (rectal exam)
Anthropometrics
Management of infant dyschezia
Avoid rectal stimulation and use of laxatives
Functional constipation Dx criteria
Must include 1 month of at least 2 of the following in infants up to 4 years of age
- = 2 defecations per week
- at least 1 episode per week of incontinence after acquisition of toileting skills
- Hx of excessive stool retention
- Hx of painful or hard bowel movements
- Presence of a large fecal mass in the rectum
- Hx of large-diameter stools that may obstruct the toilet
Functional constipation typically occurs in any of the three periods
- in infants with hard stools, often following dietary change
- in toddlers acquiring toilet skills and find defecation painful
- as school starts and children avoid defecation
PE of functional constipation
Incontinence, fecal soiling, palpating fecal mass, rectal exam
Tx of functional constipation
Family education
Avoid coercive toilet training tactics
Stool evacuation: mineral oil, lactulose, polyethylene glycol
Behavior modification
Developmental issue and not a disease
Involuntary return of previously swallowed food or secretions into or out of the mouth
Infant regurgitation
Retrograde movement of gastric contents and out of stomach
GER
RF of infant regurgitation
Prematurity
Developmental delay
Congenital anomalities of the oropharynx, chest, lungs, CNS, heart GIT
Milk allergy
Infant regurgitation Dx criteria
Both in healthy 3 week to 12 months of age
- regurgitation of 2 or more times per day for 3 or more weeks
- no retching, hematemesis, aspiration, apnea, faillure to thrive, feeding or swallowing difficulties
Infant regurgitation s/sx that need further evaluation
Failure to thrive Hematemesis FOBT Anemia Food refusal Swallowing difficulties Persistence > 1 year of age
Management of infant regurgitation
Effective reassurance
Symptom relief
Improved maternal-child interaction
FGIDs in children and adolescents
Functional dyspepsia Irritable bowel syndrome Abdominal migraine Childhood functional abdominal pain Childhoold functional abdominal pain syndrome Constipation and incontinence
Most common FGID in children and adolescents
Irritable bowel syndrome
Cyclic vomiting Dx criteria
All
- 2 or more periods of intense nausea and unremitting or retching lalsting hours to days
- return to usual state of health lasting weeks to months
Recurrent, stereotypic episodes of intense nausea and vomiting
Begins at the same time of the day
Prompt recovery
Cyclic vomiting
Tx for frequent, severe and prolonged episodes
Amitriptyline, pizotifen, cyproheptadine, phenobarbital, propanolol
Avoid food, emotional and physical stressors
Treatment during prodrome
Ondansetron to reduce nausea/vomiting
H2 blockers/PPI
Deep sedation: lorazepam
Treatment during attack
Sedation
IVF, electrolytes, H2 blockers
Functional constipation Dx criteria
Must include 2 or more in a child with a developmental age of at least 4 years
- 2 or fewer defecations in the toilet per week
- at least 1 episode of fecal incontinence per week
- Hx of painful or hard bowel movements
- presence of a large mass in rectum
- Hx of large diameter stool that may obstruct the toilet
PE of functional dyspepsia
Exam of perineum and perianal area
Rectal exam
Treatment of functional dyspepsia
Address myths and fears
Manage fecal impaction
Stool softeners preferred over laxative
Rewards for success in toilet training
Persistent or recurrent pain centered in upper abdomen
Not relieved by defecation or associated with change in form or frequency of bowel action
Functional dyspepsia
Abdominal discomfort or pain associated in 25% of the time or more, with 2 or more of:
- improvement with defecation
- change in frequency of stool
- change in form or appearance of stool
Irritable bowel syndrome
Episodic or continuous abdominal pain
Insufficient criteria for other functional GI disorders
Functional abdominal pain
Functional abdominal pain with one or more of the following:
- some loss of daily functioning
- additional somatic symptoms (headache, limb pain, sleep difficulty)
Functional abdominal pain syndrome
Paroxysmal episodes of intense periumbilical pain lasting 1 or more hours (2 or more times in the preceding 12 months)
Healthy in between for weeks or months
Interferes with normal activities
Abdominal migraine
Abdominal migraine pain is associated with 2 or more of:
Anorexia Nausea Vomiting Headache Photophobia Pallor
RF of abdominal pain-related in FGID
Parental anxiety in the first year of life
Family facotrs
Appears to be beneficial for abdominal migraine
Pizotifen