03 Deceased Donor Selection Flashcards

1
Q

Within a transplant center, dDetermination of donor exclusion criteria is based upon…

A
  • your own center’s protocols.
  • Each center can set their own criteria.
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2
Q

The new Donor Risk Criteria applies to events that have ocurred within how many days?

A

30 days before organ procurment.

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3
Q

A Risk Criteria Donor includes someone who has had sex (i.e. any method of sexual contact, including vaginal, anal, and oral) with a person known or suspected to have…

A

HIV, HBV, or HCV infection.

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4
Q

A Risk Criteria Donor includes a man who has had sex…

A

with another man.

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5
Q

A Risk Criteria Donor includes someone who has had sex in exchange for…

A

money or drugs.

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6
Q

A Risk Criteria Donor includes someone who has had sex with a person who…

A

had sex in exchange for money or drugs.

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7
Q

A Risk Criteria Donor is someone who had drug injection for…

A

non-medical reasons.

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8
Q

A Risk Criteria Donor is someone who has had sex with a person who injected drugs for…

A

non-medical reasons.

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9
Q

A Risk Criteria Donor is someone who was incarcerated (confinement in jail, prison, or juvenile correction facility) for…

A

> or = 72 consecutive hours.

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10
Q

A Risk Criteria Donor includes a child breastfed by a mother with

A

HIV infection.

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11
Q

A Risk Criteria Donor includes a child born to a mother with

A

HIV, HBV, or HCV infection.

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12
Q

A Risk Criteria Donor includes someone with unknown…

A

medical or social history.

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13
Q

Per OPTN Policy, __________ makes the decision to accept/decline an organ

A

The transplant physician, not the coordinator

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14
Q

An offer must be acknowledged within _____ hour(s) or your patient will be bypassed.

A

one

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15
Q

If the minimum offer requirements have been met by the OPO, but you would like more information how long from the original offer time do you have to decide?

A

the one hour rule (from original offer time) still applies

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16
Q

6 Required Deceased Donor Information for all organs includes:

A
  • Age
  • Cause of Death
  • Gender
  • Geographic location of donor
  • Blood and urine cultures
  • Infectious Disease testing
17
Q

6 Required Infectious Disease testing for ALL organs includes:

A
  • HIV: NAT and antibody (anti-HIV)
  • HBV: NAT, total anti-HBc, and HBsAg
  • HCV: NAT and anti-HCV
  • Syphilis donor screening or diagnostic test (DT)
  • Cytomegalovirus (CMV) antibody (anti-CMV) donor screening or DT
  • Epstein-Barr Virus (EBV) antibody (anti-EBV) donor screening or DT
18
Q

8 items Required for Deceased Kidney Donors includes:

A
  • Donor name, ID, and ethnicity
  • Date of admission for the current hospitalization
  • Relevant past medical or social history
  • Current history of abdominal injuries, operations, or abnormalities (blood vessels, ureters, or kidney)
  • Current history of avg blood pressure, hypotensive episodes, avg urine output, and oliguria
  • Current medications and transfusion history Indications of sepsis
  • HLA information
  • Recovery information
19
Q

Required HLA information for Deceased Kidney Donors includes which antigens and splits for all loci?

A

A, B, Bw4, Bw6, C, DR, DR51, DR52, DR53 and DQB

20
Q

6 Required Recovery information for Deceased Kidney Donors includes:

A
  • Final urinalysis
  • Final blood urea nitrogen (BUN)
  • Final Creatinine
  • Recovery Blood Pressure and urine output
  • Recovery medications, type of recovery procedure, flush solution and method, flush storage solution
  • Warm ischemia time, organ flush, cold ischemia
21
Q

8 Required information for Deceased Liver Donors includes:

A
  • Donor ID, and ethnicity
  • Height and weight
  • Vital signs including blood pressure, heart rate, and temperature
  • Social history, including drug use
  • History of treatment in hospital including current medications, vasopressors, and hydration
  • Current history of hypotensive episodes, urine output, and oliguria
  • Indications of sepsis
  • Liver specific lab values
22
Q

10 Required lab values for Deceased Liver Donors includes:

A
  • Aspartate aminotransferase (AST)
  • Alanine aminotransferase (ALT)
  • Alkaline phosphatase
  • Bilirubin
  • Creatinine
  • Hemoglobin (hgb) and hematocrit (hct)
  • International normalized ratio (INR)
  • Prothrombin (PT)
  • Partial thromboplastin time (PTT)
  • White blood cell count (WBC)
23
Q

11 Required information for Deceased Heart Donors includes:

A
  • Height and Weight
  • Vital signs, including blood pressure, heart rate, and temperature
  • History of treatment in hospital including vasopressors and hydration
  • Cardiopulmonary, social, and drug activity histories
  • Details of any documented cardiac arrest or hypotensive episodes
  • 12-lead interpreted electrocardiogram
  • Arterial blood gas results and ventilator settings
  • Troponin
  • Cardiology consult or echocardiogram, if the hospital has the facilities
  • Human leukocyte antigen (HLA) typing if requested by the transplant hospital, including A, B, Bw4, Bw6, C, DR, DR51, DR52, DR53, and DQB antigens
  • Toxoplasma antibody (Ab) test result or an appropriate donor sample sent with the heart for testing at the transplant hospital
24
Q

12 Required information for Deceased Lung Donors includes:

A
  • Height and Weight
  • Vital signs, including blood pressure, heart rate, and temperature
  • History of treatment in hospital including vasopressors and hydration
  • Smoking history
  • Cardiopulmonary, social, and drug activity histories
  • Arterial blood gases and vent settings on 5 cm/H20/PEEP including PO2/FiO2 ratio and 100% FiO2, within 2 hours prior to the offer
  • Bronchoscopy results
  • Chest x-ray interpreted by a radiologist or qualified physician within 3 hours prior to the offer
  • Details of any documented cardiac arrest or hypotensive episodes
  • Sputum gram stain, with description of sputum
  • Electrocardiogram and Echocardiogram, if the OPO has the facilities
  • HLA typing if requested by the transplant hospital, including A, B, Bw4, Bw6, C, DR, DR51, DR52, DR53, and DQB antigens
25
Q

If the OPO cannot perform a bronchoscopy, it must…

A
  • document that it is unable to provide results.
26
Q

11 Required information for Deceased Pancreas Donors includes:

A
  • Donor ID, and Ethnicity
  • Weight
  • Date of admission for the current hospitalization
  • Alcohol use (if known)
  • Current history of abdominal injuries and operations, pancreatic trauma
  • Current history of average blood pressure, hypotensive episodes, cardiac arrest, average urine output, and oliguria
  • Current medication and transfusion history
  • Pertinent past medical or social history including pancreatitis
  • Familial history of diabetes Insulin protocol Indications of sepsis
  • Serum amylase
  • HLA info: A, B, Bw4, Bw6, C, DR, DR51, DR52, DR53, and DQB antigens.
27
Q

3 items of information that may be requested for specific organs, but is not required includes…

A
  • Kidney Biopsy
  • Heart Cath
  • Lung Measurements/CT/ Mycology sputum smear
28
Q

3 Roles of the Transplant Coordinator in the offer process includes…

A
  • Reviews the donor with the Surgeon
  • Reviews the recipient with the Surgeon
  • Enters Acceptance/rejection into Unet
29
Q

The Transplant Coordinator must obtain consent from the recipient for these 2 things:

A
  • KDPI > 85%
  • If the donor tests positive for any:
    • Hepatitis B surface antigen (HBsAg)
    • Hepatitis B nucleic acid test (NAT)
    • Hepatitis C NAT
    • The donor tests positive for HIV and the transplant hospital participates in an approed variance according to policy 15.7
30
Q

The Transplant Coordinator documents the following 3 items of information has been communicated to the patient:

A
  • any Donor Risk Criteria
  • DCD Donor
  • Research protocols
31
Q

Discovery of new Donor disease or malignancy requires these 4 actions…

A
  • Notifying the recipient of risk of transmissible disease
  • Document new information in electronic health record
  • Follow a recipient who is at increased risk
  • Offer recipient additional testing, monitoring, and treatment in addition to routine follow up care.