02 Connective Tissue Flashcards
Name tissue and arrows
Embryonic Connective Tissue
Left arrows: Mesenchymal cells
Right arrow: Extracellular Matrix
Name the tissue and arrow.
Embryonic Connective Tissue
Mesenchymal cells
Name the tissue.
Embryonic Connective Tissue
Identify the tissue and where it’s found.
Loose (areolar) connective tissue
Found in the mucosa and submucosa of various organs, surrounding blood vessels, nerves and muscles.
What part of a blood vessel is made of up loose connective tissue?
Tunica adventitia of blood vessels
Identify tissue
Loose connective tissue deep to the epithelium of intestinal villi
Identify the tissue and A-E.
Loose (areolar) connective tissue
A: Fibroblasts
B: Collagen Fibers
C: Elastin Fibers
D: Mast cells
E: Ground substance
Name the tissue and A-C.
Loose (areolar) connective tissue
Identify tissue and where it’s found
Dense regular connective tissue
Found in tendons, ligaments, the cornea and fascia.
Identify the arrow. Describe Dense Regular Connective Tissue
Consists of regularly oriented parallel bundles of collagen fibers separated by linear rows of fibrocytes.
The nuclei of the fibrocytes appear linear and the cytoplasm is very difficult to see.
Identify the arrow.
Tendon
Identify the arrow. - type of CT
Ligament
Identify.
Cornea
Identify.
Fascia
Still Dense Regular CT
Identify tissue and where it is found.
Dense irregular CT
Found in the dermis layer of skin and the submucosa of the gastrointestinal tract
Identify tissue and its contents A-E.
Dense irregular CT
A: Collagen fibers
B: Blood vessels
C: Fibroblast nuclei
D: Connective tissue cell nuclei
E: Collagen fibers
Contains coarse, thick, intertwined bundles of collagen fibers arranged irregularly.
Fibroblasts are sparse separated by collagen.
Identify tissue and location.
Epidermis and Dermis (Dense Irregular CT) of Skin.
Reticular CT
Dense Irregular CT
Elastic CT
Dense Irregular CT
Identify tissue and characteristics.
Reticular CT
Characterized by abundance of reticular fibers
Reticular fibers are produced by fibroblasts (reticular cells)
Reticular fibers are thin, branched structures
Reticular CT is typically found in lymphatic tissue
Identify tissue and characteristics.
Elastic CT (upper pic of tunica adventitia of the aorta)
Characterized by abundance of elastic fibers
Elastic fibers of blood vessels are produced by smooth muscle cells
Elastic fibers form discontinuous lamellae around the lumen
Elastic CT is typically found in walls of large blood vessels and ligaments
Identify tissue and characteristics
Brown fat
Adipose Tissue
Serves primarily to dissipate energy
Made up of multilocular adipocytes
Multilocular adipocytes are mitochondria rich and have numerous lipid deposits
Identify tissue and characteristics.
White Fat
Adipose Tissue
Acts as a reserve of long term energy
Made up of unilocular adipocytes
Unilocular adipocytes have a single large fat (lipid) inclusion that pushes the nucleus to an eccentric position
What is an adipocyte?
a modified fibroblast
stores lipid, in a single vacuole (unilocular)
important for energy storage
What is another name fo white fat adipocytes based on their resemblance?
“Signet rings”
Fat and skinny people have ___________________ of adipocytes
Fat and skinny people have around the same number of adipocytes.
It’s how much fat is stored in each that matters.
These two images have the same magnification (compare nuclei)
Identify tissue.
Some white and brown fat together
Identify tissue and location.
Fat in bone marrow
What do the wrinkled cell membranes of adipocytes suggest?
Weight loss
Identify cellular component in CT
Fibroblasts
spindle-shaped cell and oval nucleus
Fibroblasts synthesize and secrete proteoglycans, glycoproteins and the precursor molecules of collagen and elastin
Fibroblst laying down collagen fibers
Fibroblasts also make elastin fibers, ground substance molecules, and more.
Identify the cellular component of CT
Collagen
three-chain fibrous protein that forms a triple-helix braided coiled coil for tensile strength
Two kinds of collagen: fibrillar and non-fibrillar
There are 5 “types” of collagen (I-V)
Identify cellular component and its characteristics.
Type I Collagen
Fibrillar
Tissue: Bone, Tendon, Dentin
Char: Banded fibers for tensile strength
Identify cellular component and its characteristics.
Type II Collagen
Fibrillar
Tissue: Hyaline and Elastic Cartilage
Char: Thinner fibrils
Identify cellular component and its characteristics.
Type III Collagen
Fibrillar
Tissue: Reticular Lamina of basement membranes
Char: Reticular fibers
Identify cellular component and its characteristics.
Type IV Collagen
Non-fibrillar
Tissue: Basal lamina
Char: Does not form bundles
Type V Collagen
Fibrillar
Tissue: Fetal amnion and chorion, muscle and tendon sheaths
Char: does not form banded fibrils