02 Congenital Factor Deficiencies

Question 1

The 3 most frequently seen inherited deficiencies of all the coagulation factors:

Answer 1

1. Factor VIII deficiency (Hemophilia A and Von Willebrand’s Disease)
2. Factor IX deficiency (Hemophilia B or Christmas disease)
3. Factor XI deficiency

Question 2

What demographic group is most often affected by Hemophilia A and B?

Answer 2

Hemophilia A and B are inherited as sex-linked recessive disorders, and affect males almost exclusively.