02 - coagulation disorders

Question 1

1-2. two causes of this?

Answer 1

1. purpura hemorrhagica
2. immune response secondary to some infections

(equine erlichisosis, EIA, immune-mediated anemia, equine viral arteritis, EEE, influenza, streptococcus)

Question 2

(coagulation disorders)

1. three causes of platelet defects?

Answer 2

1. DIC, end-stage hepatic dz, renal failure

Question 3

(coagulation disorders)

1. anticoagulant toxicosis (warfarin, brodifacoum, moldy sweet clover (dicoumarin)

these act on what enzyme?

what clotting factors are vit K dependent?

Answer 3

vitamin K epoxide reductase

2,7,9,10

Question 4

(coagulation disorders)

(clinical signs)

(vasculitis)

1. petechia, eccymoses
2. edema
3. fever, swollen limbs
4. liver, kidney, pulmonary infarcts

Question 5

(coagulation disorders)

(Cx - platelet disorders)

1. diffuse hemorrhaging from small blood vessels -> petechial hemorrhages on MM, 3rd eyelid, or sclera
2. epistaxis, occult melena, hyphema, hematuria
3. prolonged bleeding from wound or injection sites

Question 6

(coagulation disorders)

Answer 6

Question 7

Question 8

what vit K is bad for horses cause it causes renal failure?

Answer 8

vit K3

Question 9

Question 10