01-22 L3 Patho valvular heart disease Flashcards by Ahmad Saqr

Q

What is the cause

Acute Rheumatic Fever

A

Preceded by group A (Beta-hemolytic) strptococcal pharyngitis

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Q

What is observed histologically with

Acute Rheumatic Fever

A

Aschoff body (myocarditis)

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Q

Chronic Rheumatic Heart Disease

A

leads to solitary mitral valve involvement (70%)
Mitral and aortic (25%)

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Q

Most common cause of infectious endocarditis?

A

(50-70%) Streptococcus Viridans alpha-hemolytic
(10-20%) Staph aures (10-20%) & coagulase neg. species

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Q

What is the cause of non-infectious thrombotic endocarditis

A

Thrombi deposited on valves ‘marantic’ fibrin, platelets and other blood components,

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Q

What is the most common valvular disease in US?

A

Calcification of the aortic valve

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