0) Glossary Flashcards

1
Q

What is acute coronary syndromes?

A

A range of life threatening conditions from ustable angina to large myocardial infarction

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2
Q

What is afterload?

A

The force that the heart is having to work against

pressure in the aorta

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3
Q

What is angina pectoris?

A

Pain or discomfort in the chest resultin from myocardial ischaemia.
This pain can radiate to the arm, shoulder, jaw region.

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4
Q

What is aortic stenosis?

A

Stenosis/narrowing of the aortic (semi-lunar valve)

Creates a crescendo-decrescendo/early ejection systolic mumur

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5
Q

What does bradycardia mean?

A

A slower than normal heart rate

Usually <60 bpm

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6
Q

What are baroreceptors? Where are these located in the heart?

A

Pressure receptors. Arterial= high pressure sensors in the aortic arch and carotid sinus

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7
Q

What is a chronotrope? What are the different types?

A

A substance which alters the rhythm of the heart.
Positive= increase heart rate
Negative= decrease heart rate

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8
Q

What does coarctation of the aorta mean?

A

A discrete narrowing of the aorta near to the site of the ductus arteriosus. Can be preductal or postductal (most common)

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9
Q

What is contractility?

A

The force of contraction for a given myocardial fibre length.
An increase in C would be seen as an increase in the slope of the rsisng phase of the starling curve.
Positive inotropes such as noradrenaline increase contractility.

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10
Q

What is cyanosis?

A

Blue colourisation of the skin/mucous membranes due to high circulating levels of deoxygenated Hb in arterial blood.

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11
Q

What is diastole?

A

Phase of the cardiac cycle when the ventricles are filling and relaxed

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12
Q

What is dyspnoea?

A

Ana abnormal awareness of breathlessness

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13
Q

What is hydrostatic pressure?

A

The pressure in a fluid which exerts a force on the walls of the structure or vessel containing the fluid.

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14
Q

What is meant by hypertrophy?

A

An increase in organ size due to an increase in cell size (cardiac enlargement)

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15
Q

What is meant by hyperplasia?

A

An increase in organ size due to an increase in cell number

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16
Q

What is an inotrope?

A

A substance which alters the force of contraction of the heart.
A psotive inotrope increases the force of contraction by increasing myocardial contractility.

17
Q

What is the mitral valve?

A

The left atrioventricular valve- bicuspid valve

18
Q

What is mitral stenosis?

A

Narrowing of the opening of the mitral valve (bicuspid)- causes a mumur. Detected by auscultation mid-diastolic mumur at S2

19
Q

What is a mumur?

A

An addtional sound (S3) due to turbulent flow- heard on auscultation of the heart. Also hear bruit on auscultation of blood vessel.
S3 due to mitral/aortic stenosis or regurgitation.

20
Q

What occurs in myocardial ischaemia?

A

Shortage of blood flow to a region of the heart, usually as a result of partial occlusion of one of the coronary arteries.

21
Q

What is a myocardial infarction?

A

Irreversible necrosis of heart tissue due to an obstruction of a coronary vessel

22
Q

What is oncotic pressure?

A

The component of osmotic pressure due to large, non-diffusible molecules ie plasma proteins.
Artificial macromolecules given as plasma expanders (dextrans) contribute.
Also known as colloid osmotic pressure

23
Q

What is preload?

A

Related to end-diastolic volume and end-diastolic pressure. The amount of stretch (wall stress) of the myocardium at rest.
Therefore the greater the venous return, the greater the preload.

24
Q

What is systole?

A

The phase of the cardiac cycle when the ventricles are contracting to force blood from the chambers of the heart into the 2 circulations.

25
Q

What is the term for a higher than normal heart rate?

A

Tachycardia