0 Flashcards

1
Q

microangiopatia

A

nefropatia, neuropatia, retinopatia

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2
Q

macroangiopatia

A

ateroesclerose e arterioesclerose hialina

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3
Q

proteoglicanos (retenção de agua)

A

aumentam
(mixedema e osteoartroses)

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4
Q

amiloidose localizada órgãos

A

pulmão, laringe, pele, bexiga, lingua

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5
Q

amiloidose TTR órgãos

A

aorta, coração

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6
Q

complicação DM2

A

glicosilacao n enzimatica - formação de ages
ativ PKC
hiperglicemia intracelular
stress oxidativo

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7
Q

proteina al

A

cadeias leves de imunoglobolina, prod por plasmocitos, 1º

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8
Q

fibrila aa

A

doenças inflamatorias crónicas, prod figado, 2º

e febre mediterraneo familiar

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9
Q

b amilóide

A

alzheimer (placas, angiopatia e emaranhados)

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10
Q

attr

A

paf - povoa do Varzim
senil - idosos

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11
Q

amilóide endocrino - tumores

A

carcinoma medular da tiroide
tumores das ilhotas pancreáticas
feocromocitomas
carcinomas indiferenciados do estomas

nota n tumor - dm2

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12
Q

efeito do amilóide

A

perda de função
órgãos ocos- espessamento da parede
órgãos maciços - endurecimento do parenquima

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13
Q

nefropatia - dm

A

lesões glomerulares, arteriosclerose e pielonefrite

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14
Q

neuropatia - dm

A

sensibilidade em luva/meia, isquemia nas extremidades

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15
Q

retinopatia - db

A

pre proliferativa
proliferativa - fibrose e neovascularizacao
glaucoma - aum p
cataratas - ros no cristalino

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16
Q

dm 2 genes

A

hla dr3
hla dr4

17
Q

diabetes da deposição de amilina

A

2