- Flashcards

1
Q

Which type of hemorrhage is associated with a lucid interval?

A

Epidural

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2
Q

Best method of investigation of a CNS neoplasm?

A

MRI WITH CONTRAST

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3
Q

What do we give to decrease vasogenic oedema due to a brain tumor?

A

Dexamethasone

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4
Q

Management of acute onset optic neuritis?

A

Pulse steroids

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5
Q

Name 3 potentially epileptogenic drugs

A

ciprofloxacin
tramadol
anti malarial.

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6
Q

Drugs w/ important AED interactions

A

warfarin / digoxin/ oral ontraceptive / antibiotics

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7
Q

Gold standard investigation for the diagnosis of PNES?

A

Video EEG

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8
Q

Most important investigation for epilepsy

A

EEG + brain MRI

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9
Q

the single most useful laboratory study for the evaluation of patients with a suspected myopathy?

A

CK.

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10
Q

When taking muscle biopsies, which muscles should we choose?

A

UPPER EXTREMITIES: biceps
LOWER EXTREMITIES : vastus lateralis.

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11
Q

Most diagnostic investigations of DM?

A

Myositis specific autoantibodies
Muscle biopsy

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12
Q

Most diagnostic investigations of DM?

A

DermatoMyositis specific autoantibodies
Muscle biopsy

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13
Q

What muscle biopsy findings are diagnostic for dermatomyositis?

A

Atrophy in the perifasicular area.

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14
Q

Why is it important to differentiate immune mediated necrotizing myopathies from LGMD?

A

LMGD: non treatable/ non painful
immune mediated necrotizing myopathies: treatable/ painful

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15
Q

Autoantibodies in IMNM?

A

SRP + HMG-CoA reductase autoantibodies

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16
Q

Management of autoimmune myopathies? (DM/ anti syntehatse/ IMNM)

A
  • mild weakness: prednisone
  • moderate weakness: prednisone + Immunotherapy (methotrexate/ azathioprine/ microphrnylate mofetil) etc
  • cancer screening since they are common paraneoplastic syndromes.
17
Q

Diagnostic investigation of IBM?

A

MRI, shows asymmetrical muscle affection.

18
Q

Treatment of MG

A
  • Pyridostigmine (if AChR autoantibodies)
  • Plasma exchange + IVIg for exacerbation
  • PREDNISONE FIRST LINE mmunosuppressant
  • thymectomy
  • Rituximab for refractory disease
19
Q

Symptoms of Lambert Elton and its association with/ lung cancer?

A
  • gait dysfunction/lower extremity weakness,
  • areflexia or hyporeflexia
  • autonomic dysfunction.
    Associated with good prognosis is present w/ SCC.
20
Q

Inheritance pattern of dystrophinopathies?

A

X linked.

21
Q

US findings of CMT?

A

Nerve thickening

22
Q

What investigation can we use to screen asymptomatic relatives of patients of CMT

A

NC

23
Q

Is CMT demyelinating or axonal?

A

Could be both.

24
Q

Management of CMT?

A

rehabilitative and symptomatic

25
Q

Management of chronic carpal tunnel syndrome

A

Rest and splints may help.
• Diureticsandanti-inflammatorydrugs
• Steroids injection into the carpal tunnel
• Incise the transverse carpal ligament to decompress the tunnel.

26
Q

Antibodies present in MMN?

A

anti-GM1

27
Q

Management of MMN?

A

Favorable response to IVIg

28
Q

“Cytoalbuminous dissociation “ is a finding in which comditons?

A

Aseptic meningitis
GBS

29
Q

Important findings in viral meningitis?

A

Temporal love enhancement on MRI
Focal seizures (commonly of temporal lobe)

30
Q

Important findings in viral meningitis?

A

Temporal love enhancement on MRI
Focal seizures (commonly of temporal lobe)

31
Q

Important findings in viral meningitis?

A

Temporal love enhancement on MRI
Focal seizures (commonly of temporal lobe)

32
Q

What investigation should be done for suspected fungal meningitis

A

Inidia ink test

33
Q

MRI findings in bacterial meningitis?

A

Leptomeningel enhancement

34
Q

Difference in treatments of CIDP vs GBS?

A

Gbs: Plasma exchange + IVIg. DO NOT GIVE STEROIDS!!!
CIDP:
- PREDNISOLONE
- Plasma exchange + IVIg

35
Q

What is titubation a sign of?

A

Cerebellar dysfunction

36
Q

Triggers of a seizure

A

MISSED ANTIEPILEPTIC DOSE
ALCOHOL/ DRUGS
SLEEP DEPRIVATION
HYPOGLYCEMIA (skipping meals)
PHOTOSENSITIVITY ( flashing lights)
DEHYDRATION
MENSES IN SOME WOMEN

37
Q

Most important location of intra cerebral hematoma on top of hypertension?

A

Lenticulostriate arteries which supply the BG and internal Capsul The largest medial one (Recurrent artery of H𝑒ubner) is known as the artery of internal hemorrhage M.)