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Immunity > ملزمة رقم ٢ > Flashcards

ملزمة رقم ٢ Flashcards

1
Q

What are types of lymphoid organs?

A

Primary (thymus-bone marrow)

Secondary (spleen -lymph node-MALT)

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2
Q

Primary lymphoid organ function

A

In mammals, T cells mature in the thymus and B cells mature in the bone marrow.
Become mature:committed to specific antigen

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3
Q

Thymus:

A

Primary lymphoid organ

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4
Q

Thymus anatomy and location

A

• The thymus in mammals is a bilobed organ, located in the thoracic cavity , overlying the heart and major blood vessels. Each lobe is surrounded by a capsule and is divided into lobules. Each lobule is organized into cortex and medulla

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5
Q

Cortex content

A

Immature thymocyte (lack of CD44)

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6
Q

Medulla content

A

Mature thymocyte T-cell with (CD44)

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7
Q

What happens when immature cell (lack of CD44)pass to medulla

A

It’s will be destroyed via macrophages

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8
Q

Where the nurse cell located

A

Thymus (outer cortex)

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9
Q

Where epithelial cell located and features

A

1-thymus cortex (as network)

2-thymus medulla(as clusters)

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10
Q

Where APC (dendritic cell located in thymus)

A

Corticomedullary junction

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11
Q

Epithelial cell &dendritic cell express….

A

MCH ON SURFACE

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12
Q

Benfit of APC

A

Presentation of antigen to T cell

To TCELL DEVELOPMENT AND SELECTION

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13
Q

What’s the causes of thymus atrophy?

A

1-low level of steroid
2-high level of corticosteroids (cause cortical atrophy)
3-pregnancy
4-stress

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14
Q

Which part of thymus more suitable

For atrophy

A

Cortex is more atrophy

Medulla usually remain intact

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15
Q

Bone marrow information

A

Soft vascular tissue fills bone cavity of calcines bones

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16
Q

Bone marrow content

A

Heamatopoitcs cell and fat cell and osteogenic reticular cells

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17
Q

What the types of bone marrow

A

1-red marrow

2-yellow marrow

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18
Q

Red marrow content

A

1-RBC
2-WBC
3-Platelet

19
Q

Yellow marrow content

A

1-fat

2-WBC SOME TIMES

20
Q

Locations of RED MARROW

A 
Flat bones
1-hip bones
2-scapula
3-ribs
4-shoulder girdle
5-scalp etc
Spongy part of long bones
1-femur 
2-tibia
Proximal and distal part
21
Q

Secondary lymphoid organs

Spleen

A

Secondary lymphoid organ

Blood-bron antigen

22
Q

Spleen content

A

1-red pulp

2-white pulp

23
Q

Red pulp content

A 
1-venous sinuses 
2-cellular cords
3-RBC
4-WBC
5-platelet 
6-granulocyte 
7-lymphocytes
24
Q

White pulp?

A

Contain mainly lymphoid tissue

25
Q

T-cells location in spleen

A

PAS(peri arteriolr lymphoid sheath )

Around central arteriolar )

26
Q

B -cell location

A

At periphery

27
Q

B cell arangment in B-ell

A

1-Primary lymphoid follicle

2-secondary lymphoid follicle

28
Q

What the difference between them

A 
Primary is  un stimulated 
1-no germinal center 
2-no memory cells
Secondary 
1-with germinal center 
2-with memory cells
29
Q

What function of spleen

A

Destroyed aged platelet and RBC

Via hemocatheresis

30
Q

Lymph node function

A

Is important for taken antigen from interstitial part to thoracic lymph nodes

31
Q

Lymph nodes locations

A 
1-neck
2-medistenum 
3-abdominal cavity
4-groin rigion 
5-axillary regoin
32
Q

Types of lymph node of skin

A 
Super fascial (company with  vens )
Deep (company with artery)
33
Q

Structure of lymph nodes

A

Kidney shaped structure covered with collagens capsule and received blood via afferent arteriole
And pass blood via efferent arteriole
With hillus when bloo vessel’s pass

34
Q

In lymph node Tcell location

A

Para cortical area

35
Q

B-cells location

A

Cortex

36
Q

Plasma cells

A

Medulla

37
Q

Epithelial cell with dendritic cell contain

A

MHC2

38
Q

Malt

A

Is non capsulate lymphoid tissue

39
Q

Location of it

A

1-Respiratory tract
2-GIT
3-GUT
4-TONSILS

40
Q

Payers patches

A

Is diffuse lymphoid tissue that located in GIT AND GUT AND CONTAIN M CELL THAT TRAPPED PATHOGEN TO UNDERLYING PLASMA WITH MACROPHAGE AND DENDRITIC CELL AND T CELL

41
Q

Tonsils

A

Lymphoid tissue aggregations

42
Q

Location of tonsils

A

1-palatine tonsil( oropharynx )
2-pharyngeal tonsil (adenoid)
3-lingual tonsil

43
Q

What tonsil conten

A

Secondary lymphoid folicle and endothelial venule

Immunity (1 decks)

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