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Фармацевтична Химия > Бсрбитурати > Flashcards

Бсрбитурати Flashcards

1
Q

What are barbiturates primarily used for?

A

Barbiturates are primarily used as sedatives, anesthetics, and anticonvulsants.

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2
Q

True or False: Barbiturates are a class of drugs that can lead to physical dependence.

A

True

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3
Q

Fill in the blank: The chemical structure of barbiturates is based on the _____ molecule.

A

barbituric acid

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4
Q

What is the chemical formula for barbituric acid?

A

C4H4N2O3

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5
Q

Which of the following is a common barbiturate? A) Diazepam B) Phenobarbital C) Zolpidem

A

B) Phenobarbital

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6
Q

What is the chemical formula for Phenobarbital?

A

C12H12N2O3

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7
Q

True or False: Barbiturates can be used for treating insomnia.

A

True

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8
Q

Name one side effect of barbiturate use.

A

Respiratory depression

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9
Q

What is the primary mechanism of action for barbiturates?

A

They enhance the activity of the neurotransmitter GABA.

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10
Q

Fill in the blank: Barbiturates are classified as _____ drugs.

A

central nervous system depressants

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11
Q

What is the chemical formula for Amobarbital?

A

C11H18N2O3

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12
Q

True or False: Barbiturates have a narrow therapeutic index.

A

True

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13
Q

What is the chemical structure of barbiturates derived from?

A

Ureide of malonic acid and urea.

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14
Q

Which barbiturate is commonly used for euthanasia in animals?

A

Pentobarbital

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15
Q

What is the chemical formula for Secobarbital?

A

C11H16N2O3

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16
Q

Fill in the blank: Barbiturates can cause _____ when taken in overdose.

A

coma or death

17
Q

What is the role of barbiturates in modern medicine?

A

They are mostly replaced by benzodiazepines but still used in specific cases.

18
Q

Name a barbiturate that is often prescribed for anxiety.

A

Butabarbital

19
Q

What is the chemical formula for Thiopental?

A

C11H18N2O2S

20
Q

True or False: Barbiturates are often used in combination with other medications.

A

True

21
Q

What type of barbiturate is often used for induction of anesthesia?

A

Thiopental

22
Q

What is the primary risk associated with barbiturate use?

A

Overdose leading to respiratory failure.

23
Q

Fill in the blank: Barbiturates can interact with _____, increasing the risk of overdose.

A

alcohol

24
Q

What is the chemical formula for Pentobarbital?

A

C11H18N2O3

25
Q

True or False: Barbiturates can be used to treat epilepsy.

A

True

26
Q

What is a major reason for the decline in barbiturate prescriptions?

A

The development of safer alternatives like benzodiazepines.

27
Q

What is the effect of barbiturates on sleep patterns?

A

They can alter normal sleep architecture.

Фармацевтична Химия (1 decks)

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