SBM I.D.

1. Identify the major infectious pathogens causing acute pharyngitis, acute bronchitis, and acute bacterial sinusitis. 2. Understand the clinical presentations of the principle syndromes associated with pharyngitis, bronchitis, and sinusitis. 3. Understand the differing biological pathways to clinical illness: receptor-mediated release of kinins in colds; invasive pyogenic bacterial infection with acute sinusitis; and immune-mediated rheumatic sequela in streptococcal pharyngitis. 4. Become f

• Describe the pathogens that cause different types of pneumonia and the drugs that treat them • Identify the geographic, behavioral and social factors that predispose to pneumonia • Recognize the clinical manifestations, diagnosis and treatment of pneumonia • Recognize the critical role of chest radiography in the diagnosis of pneumonia • Review the role of vaccination in the prevention of pneumonia • Review behavioral risk factors for pneumonia such as alcohol abuse • Identify the role o

I. To understand the basic defense mechanisms against infection and what defines a compromised host II. To understand the importance of determining host immune status in the assessment of infectious disease management III. To understand the types of infections associated with specific immune defects IV. To review some diagnostic, therapeutic and preventive modalities for the care of the compromised host.

To be able to name the diseases caused by the four most important systemic fungal pathogens, and one emerging disease, where they are found, their clinical symptoms, when they should be considered in diagnosis, and how they are treated.

I. To understand the meaning of the expression “opportunistic infection,” in terms of host factors and microbial pathogenesis. II. To become familiar with clinical circumstances predisposing to infections caused by Candida, Aspergillus, the Zygomycetes, and Cryptococcus. III. To understand the role of phagocytes and cellular immunity in defense against opportunistic fungi. IV. To be familiar with the diverse clinical manifestations of infection with opportunistic fungi, with diagnostic method

A. Understand the spectrum of infectious causes of meningitis. B. Understand the pathophysiology of bacterial meningitis, including the effect of infection on cerebral blood flow. C. Understand the importance of early recognition of meningitis and the approach to diagnosis and management.

•To differentiate the clinical signs and symptoms and treatment of meningitis, encephalitis, myelitis, and focal central nervous system (CNS) infections •To identify the major pathophysiologic mechanisms and representative organisms associated with viral encephalitis

DESCRIBE the predominant causes of sepsis, and the antibiotic and other treatments of sepsis REVIEW the epidemiology of sepsis REVIEW the clinical manifestations, diagnosis and treatment of sepsis DESCRIBE the role of imaging in the evaluation of patients with sepsis REVIEW the role of drainage of pus in the management of sepsis DESCRIBE the role of body fluid cultures and common imaging modalities in the systematic work up of sepsis

1. Recog epidem and med behaviors that give rise to healthcare-assoc infxs 2. ID manifestations, DX and Px of common healthcare-assoc infxs 3. Review public health impact of HCAI, and the std px measures taken to address them 4. Recog the critical role or px in the containment of HCAI 5. Recog their economic impact 6. Describe the role of culture techniques in the dx of HCAIs 7. ID the role of the MD in px and containment of HCAIs