This class was created by Brainscape user Livia Ng. Visit their profile to learn more about the creator.

Decks in this class (25)

NaV Localization
What 2 properties of nav15 contri...,
What 4 diseases are linked to nav14,
Which nav are present in cns duri...
15  cards
NMDA Subunit Composition
What are the families of subunits...,
What do nmda heterotetramers cons...,
How many glun2 subunits are there...
8  cards
NMDA Biophysical Properties
Key biophysical properties and si...,
What do nmdars mediate at excitat...,
Describe nmdar activation time co...
20  cards
NMDA Mg2+ + Ca2+
Briefly outline nmdar activation ...,
What is the importance of steep v...,
What does selectivity for mg2 and...
16  cards
NMDA Pharmacology
What is the nature of ntd and lbd...,
What confers proton sensitivity,
What is the mechanism of action o...
6  cards
IP3 PLC + PKA
What do heterotrimeric g proteins...,
How do g proteins dissociate,
What underlies gpcr intracellular...
14  cards
IPC IC Ca2+ Signalling
0  cards
IPC Time Course
Ca2 concentration in er lumen vs ...,
What maintains ca2 concentration ...,
In what way is serca ca2 sensitive
15  cards
GPCR Cycle
The main feature of gpcrs,
What do gpcrs bind,
How do ligands typically bind to ...
17  cards
GPCR βγ Regulation
What was the initial model of gpc...,
What and who challenged the initi...,
Who and how were initial findings...
24  cards
GPCR βγ Spatiotemporal
What do gaps do,
What are the downstream effects o...,
How do g s interact with gaps
14  cards
NaV Inactivation
Why is inactivation of nav important,
Types of inactivation,
How does the voltage sensor relat...
14  cards
NMDA Pharmacology 2
What is an example of a non selec...,
What is an example of a glun2b sp...,
With what affinity does ifenprodi...
16  cards
PIP2 Basics
What are phosphoinositides,
What is the parent compound of ph...,
What gives rise to variations in ...
11  cards
PIP2 Kir's
Which channels were first recogni...,
What kind of channels are kir6xs,
How has kir channel pip2 activity...
22  cards
PIP2 KCNQ
What are kcnq channels,
Why are kcnq channels significant...,
How are kcnq currents affected by...
16  cards
PIP2 PLC
What is the significance phosphol...,
What do plc s do in gpcr pathways,
What are plc s stimulated by
10  cards
PIP2 Membrane Levels + PIP3
What does pip2 concentration act ...,
How is pip2 resynthesised,
How do ca2 i signals impact pip2 ...
14  cards
NMDA Revision
Who characterised the activation ...,
What does characterisation of act...,
What times time for nmdar to be o...
21  cards
NMDAR revision 2
What is the ec50 of glutamate bin...,
What does the addition of exon5 d...,
How do heterotrimeric glun1 2a 2b...
22  cards
GIRK Revision
How do gpcrs bind ligands,
How does ligand binding generate ...,
G proteins are heterotrimeric pro...
32  cards
Sodium Revision
First evidence that ttx was a nav...,
Structural determination,
External block
34  cards
PIP2 Revision
Phosphoinositides are,
Parent compound of phosphoinositides,
Phosphoinositides 3 functionsq
39  cards
Potassium structure
Selectivity filter,
What varies between kvs,
Similar features of kvs
34  cards
K+ Pharma
Type a blocker,
Where does discrepin bind,
Kv7 blocker
17  cards

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Receptor Mech

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