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Libby Madden
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Decks in this class (34)
lecture 2 membrane transport
How does a g protein work,
Macro transfer,
Micro transfer
22
cards
lecture 3 - membrane transport
P type atpases,
Na k pump,
1 na enters the channel2 conforma...
20
cards
lecture 4 - epithelia
Determinants of permeability in r...,
Passive diffusion permeability,
What does lp stand for
23
cards
lecture 5/6- Molecular Mechanisms of Epithelial Ion and Fluid Transport
Movement of sodium outside to inside,
Movement of chloride from outside...,
Water follow the nacl by
29
cards
lecture 7 - cystic fibrosis
What is cftr,
The most common mutation is,
Class i no protein
19
cards
lecture 8/9 - CF part 2
Sweating,
Sodium transport drives the chlor...,
Gene therapy
19
cards
lecture 12 - broad principles of cell signaling
Why is cell signalling important,
Cell signaling effects,
Cells respond to
24
cards
lecture 13 - ligand gated ion channels
Neurotransmitters,
Agonists,
Antagonists
22
cards
lecture 14 - ligand gated ion channels (glutamate)
Glutamate,
Three main classes of glutamate r...,
Glutamate vinds to ampars and nmd...
16
cards
lecture 16 - the phosphoinositide signalling pathway and Ca2+
Calcium prevents polysperming by,
Calcium phosphate is highly insolube,
Off mechanisms
11
cards
lecture 17
What hormone signals the pi pathway,
Calcium spikes persist for as lon...,
Calcium released from the er feed...
11
cards
lecture 18
Elementary events,
A calcium puff is,
Calcium release from a cluster of...
10
cards
lecture 19
Heterogeneity,
Cell specific calcium signalsome,
Signalsomes can be remodeled altered
14
cards
lecture 20 - G protein coupled receptors and cAMP signalling
On mechanism camp production,
Plant alkaloid activates the enzyme,
Some are regulated by calcium if ...
18
cards
lecture 21 - dynamics of cAMP signalling
Problem for camp is that there ar...,
High fret when,
When you increase camp you get le...
12
cards
lecture 22- other protein kinases and protein phosphatases
Protein kinases activated by cycl...,
Other protein kinases activated b...,
Cgmp signalling pathway
18
cards
lecture 23 - blood glucose homeostasis and insulin action
Insulin is secreted in conditions of,
Insulin lowers,
Glucagon in secreted in condition...
32
cards
lecture 24 - insulin signalling
Protein domain ph,
Ptb domain,
Sh2 domain
23
cards
lecture 25 - drug targets for treating type 2 diabetes
Type 2 diabetes,
Obesity in associated with insuli...,
Calorie excess and physical inact...
20
cards
lecture 7 - redone
What is cftr,
What is the most common mutation,
What is class 1 mutation
30
cards
lecture 5/6 - redone
Sodium movement outside to inside...,
Sodium movement out the cell,
Movement of chloride
48
cards
lecture 8/9 redone
In cf you cant reabsorb sodium ch...,
What is n in n x po x i,
Po
9
cards
lecture 12 redone
Camp signalling pathway signal mo...,
The g protein turns on,
Adenylyl cyclase converts atp to
6
cards
lecture 13 redone
Agonists,
Antagonists,
What is the major excitatory neur...
17
cards
lecture 14 redone
Glutamate is a,
Glutamate binds to,
Are nmda receptors or ampa recept...
15
cards
lecture 16 redone
Calcium prevents polyseprming by,
Why is calcium used in so many pr...,
Off mechanism 1 ca atpase pump pm...
18
cards
lecture 17 redone
What hormone signals the pi pathway,
If you double the concentration o...,
What is cicr
7
cards
lecture 18 redone
A calcium puff is,
A calcium spark is,
Smaller event than an elementary ...
10
cards
lecture 19 redone
Heterogeneity,
2 types of remodelling,
Phenotypic remodelling
29
cards
lecture 20 redone
On mechanism camp production camp...,
There are 2 different types of ad...,
What domains to type 1 have
17
cards
lecture 22 redone
What protein kinase is activated ...,
What protein kinases are activate...,
Cgmp signallin pathway gpcrs aren...
6
cards
lecture 23 redone
Insulin is secreted in conditions of,
Insulin lowers,
Glucagon is secreted in condition...
55
cards
lecture 24 redone
Ph domain proteins with ph domain...,
Ptb domain,
Sh2 domain 2 domain binds phospho...
27
cards
lecture 25 redone
Robust beta cells increase insuli...,
Target carbohydrate absorption en...,
Inhibitors of this enzyme have be...
11
cards
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PCS2002
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