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Fumeng Sun
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Decks in this class (38)
1-intro to immunology
What is immunology 1,
What does vaccine do to immune re...,
A properly functioning immune sys...
5
cards
2-overview of immune system I
4 major categories of pathogens i...,
Different pathogens require 2,
A major difference is between mic...
41
cards
3-overview of immune system II
Innate immunity timing uses recep...,
Adaptive immunity timing uses rec...,
Phases of the immune response 3
28
cards
4-Innate Immunity I (Basics: Tissues, cells & molecules )
Pathogen enter through 1,
To cause infection 2,
Epithelial surfaces of the body a...
32
cards
5 – Innate Immunity II
What is th complement system 1,
Complement systems are mostly 2,
Most complement are called 3
51
cards
6 – Innate Immunity III
What are pamps 1,
Pamps recognized by 2,
What are prrs 3
37
cards
7 – Innate Immunity IV (Signaling & Cell migration)
4 effects of prr signaling 1,
Pro inflammatory cytokines 2,
Potent antiviral cytokines 3
32
cards
8 – Innate Immunity V
Cytokines are 1,
Cytokine production 2,
Cytokine provides 3
47
cards
9 – Innate Immunity VI (ILCs & NK cells)
Nk cells 1,
How many types of ilc is there 2,
Cytokines can influence 3
23
cards
Innate Immunity Module summary
Key cells 1,
Key tissues 2,
Key molecules 3
4
cards
10 – Linking Innate & adaptive: Traveling to lymphoid tissues
Dcs travel from to 1,
Activated dcs travel via to 2,
Activated dcs express to 3
26
cards
11 – linking innate & adaptive:Visualizing antigen presentation
Dcs can present multiple 1,
Run down of dc activation 2,
Selectin 3
29
cards
12 – linking innate and adaptive:TCR, MHC & co-receptors
Tcr recognizes peptide mhc pmhc c...,
Recognition leads to 2,
Recognition requires 3
41
cards
13 – linking innate & adaptive: Antigen processing
Mhc class i presentation require 1,
Mhc class ii presentation require 2,
Endogenous pathogens examples 3
30
cards
14 – Linking innate & adaptive: Exceptions & MHC genetics
3 exceptions 1,
Cross presentation by 2,
Cross presentation by dcs example 3
32
cards
15 – Linking Innate & adaptive: Signals 1 & 2
Antigen presentation 3 signals 1,
Receptors for 2,
2 types of receptors what are they 3
26
cards
16 – Linking innate & adaptive: T cell proliferation (signal 1 & 2)
Il 2 induces 1,
Il 2 example of 2,
Il 2 proliferation outcome 3
14
cards
Linking innate & adaptive immunity Module summary
Key cells 1,
Key tissues 2,
Key molecules 3
7
cards
17 - T cells I : Module intro/overview & signal 3: T cell differentiation
Where is signal 3 1,
T cell exert their function is al...,
Once infection cleared there are 3
35
cards
19 - T cells II: CTLs & cytokine patterns
Fas ligand cd40 ligand both expre...,
Ligands crucial for 2,
Fas ligand cd40 ligand are ligand...
45
cards
20 - T cells III: CTL, cytokine pattern, cross-regulation/recrptors/homing & Th1
Effector cd4 t cell subsets funct...,
Th1responses 2,
Th2 responses 3
30
cards
21 -T cells IV: Th1 & Th2 cells
Th1 signal 3 polarizing cytokines 1,
Th1 transcription factors 2,
Th1 master transcriptional regula...
45
cards
23 - T cells V: Th17 cells
P00th17 cells type 3 response 1,
Th17 cells type 3 response 2,
Th17 cells type 3 response 3
29
cards
24 - T cells VI: TFH, negative regulation & Tregs
Tfh signal 3 1,
Tfh transcription factors 2,
Tfh master transcriptional regula...
56
cards
26 - B cells: Overview of adaptive immunity, B cells & B cell activation (Signal 1&2)
Antigen presentation in 1,
Activation of b signal 1 2,
Activation of b cells via tfh sig...
42
cards
28 - B cells: B cell activation: primary focus & germinal center
Where do all interactions happen ...,
Subcapsular sinus 2,
T cell zone 3
21
cards
29 - B cells: Antibody structure/binding/different classes
Structure of immunoglobulin ab 1,
Immunoglobulin ig the specific ch...,
Both heavy light chain have a 3
37
cards
30 - B cells: Generation of BCR diversity
Primary diversity primary diversi...,
Heavy chain light chain gene fami...,
Variable region of ig ig gene div...
34
cards
31 - B cell: Generation of TCR diversity, Ig isotopes
Tcr structure 1,
Somatic recombination takes place...,
Combinatorial diversity of tcr 3
25
cards
32 - B cells: Germinal Center
2 zones in germinal center 1,
What happens in what is found in ...,
What happens in germinal center 3
25
cards
33 - B cells: B & T cell Memory, immunization
B cell memory quantitative qualit...,
B cell memory quantitative qualit...,
Repeated immunization leads to 4 3
28
cards
34 - B cells: Distribution & function of antibodies
It is well documented that antibo...,
Antibodies mediate 2,
Key ab functions 5 3
42
cards
35 - B cells:Lymphocyte development
Tolerance 1,
How does self reactive happen 2,
Tolerance helps to 3
43
cards
36: review & questions
The kinetics of a typical cd8 t c...,
When macrophages in a tissue enco...,
Individuals or mice with defects ...
9
cards
Guest speaker – Auto-immunity: Multiple Sclerosis
What type of disease is multiple ...,
What happens to the myelin sheath...,
What is sclerosis in the context ...
18
cards
Guest speaker -IPT Immunology
What is immune thrombocytopenia i...,
What are the environmental causes...,
What genetic predispositions are ...
14
cards
Guest speaker – cancer immunology research
What is immune surveillance 1,
What is immune evasion in the con...,
Define anti tumor immunity 3
7
cards
Guest speaker – studying T cell localization in solid tumors
What is the cancer immunity cycle 1,
What characterizes an immune dese...,
What is an immune excluded tumor 3
20
cards
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