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deniz amk
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Decks in this class (25)
biomarkers and drug targets
Identify the leading causes of death,
Define the term biomarker,
Identify how drug efficacy can be...
6
cards
drug absorption
Describe routes of drug administr...,
Describe anatomy and physiology o...,
Describe the mechanism of oral dr...
8
cards
voltage gated ion channels
Identi,
What is the general structure of ...,
What is the effect of local anaes...
10
cards
Ligand gated ion channels
Which ion for lgics,
Families of lgics and their struc...,
Therapeutic exploitation of p2x
13
cards
Elimination
Clearance,
Liver physiology,
Hepatic elimination
18
cards
Catalytic receptors
Catalytic receptor families,
Receptor guanylyl cyclase structure,
Rgc function
13
cards
nuclear hormone receptors
What are the main groups in the n...,
What do zinc fingers in the dbd c...,
What are the hormone response ele...
20
cards
Distribution
Vessels in distribution,
Determinants of rate of distribution,
Bbb distribution
8
cards
NCA
Nca overview,
Auc aumc and kel
2
cards
GPCR structure
Classes a f,
Rhodopsin like,
Secretin adhesion
10
cards
GPCR signalling
Na binding,
G protein coupling,
G protein structure
9
cards
compartmental PK
What is the effective dose and wh...,
What are the components of compar...,
What is the rate of drug absorpti...
8
cards
transporters
What are the three major families...,
What are characteristics of p typ...,
What are some examples of p type ...
9
cards
in vitro DMPK
How is oral absorption predicted,
How is absorption modelled in vit...,
What does pampa estimate
16
cards
drug interactions
Types of ddis,
Anti hiv drugs use of ddis,
Cyp inhibition ddis
8
cards
interindividual variability in PK
What factors lead to differences ...,
How does pregnancy effect pk betw...,
How does ethnicity effect pk betw...
9
cards
enzymes
Pro drugs,
Proteases,
Kinases
8
cards
DILI
Metabolic dili,
Immunologic dili,
Risk factors
7
cards
Liver structure and function
Roles,
Liver lobule,
Liver disease phase
12
cards
PK/PD
What is pk pd modelling,
What are in silico experiments,
What do pk pd graphs include
13
cards
Atypical drugs
Tubulin inhibitors,
Cereblon inhibitors,
Drugs with unknown moa
11
cards
chronic therapy
What are some examples of drugs w...,
What is the mechanism of adaptati...,
B2 ar uncoupling
8
cards
smooth muscle function
How smooth muscles contract,
Initiation of smooth muscle contr...,
Sustained sm contraction
11
cards
neuronal function
Ach lifecycle,
Na lifecycle,
Presynaptic receptors
10
cards
Drug examples for each lecture
Biomarkers and drug targets drug ...,
Drug examples for vgics,
Drug examples for lgics
15
cards
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mechanisms of therapeutic drugs
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