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Allison Vise
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Decks in this class (77)
LEC1: pH and Buffers
Where can pka be useful,
Formula for dissociation constant...,
How do weak acids abses act as bu...
36
cards
LEC2: Amino Acids and Proteins
Explain the naming of carbons in ...,
Which conformation of proteins ar...,
How are amino acids classified
82
cards
LEC3: Protein Structure and Ligand Binding
Why is the bind of a ligand to its,
For a drug that binds to a receptor,
How would removing the tetrameriz...
32
cards
LEC4: Lipids and the Plasma Membrane
What are lipids,
How,
Saturated vs unsaturated fatty acid
50
cards
LEC5-8: Signal Transduction
What is signal transduction,
General categories of cell cell s...,
Types of signaling factors
79
cards
LEC9-11: Enzymes & Enzyme Kinetics
What does it mean that biochemica...,
If combined free energy of x y is...,
What is the formula for keq of th...
80
cards
Amino Acids
Alaninealaanon polar
15
cards
LEC12-13: Pharmacodynamics I & II
Whats the broad definition of a drug,
What is pharmacodynamics,
What is pharmacokinetics
50
cards
LEC14: Introduction to Electrophysiology
What types of membrane proteins a...,
How do carrier proteins work,
How do channels work broadly
23
cards
LEC15: Carrier Proteins
What is passive membrane behavior,
What is active membrane behavior ...,
What kind of transport do pumps do
28
cards
LEC16: Ligand-Gated Channels
What differentiates channels by s...,
What regulates most channels,
What kind of modulation do ligand...
25
cards
LEC17: Voltage-Dependent Channels
What are the classes of voltage d...,
What is the structure of inward r...,
What is the p loop of the inward ...
19
cards
LEC18: Membrane Excitability
What is passive membrane behavior,
What kind of channels are in memb...,
How do excitable membranes show a...
32
cards
LEC19: Voltage-Clamp and Patch-Clamp
Why cant you use a current clamp ...,
How does a voltage clamp work,
What is the sign of an inward out...
16
cards
LEC20: Channel Regulation by Second Messengers
What is,
Where is ca2 sequestered in cells,
What are the different triggering...
32
cards
LEC21: Overview of Gene Expression; Nucleic Acid Structure
Almost all somatic cells contain ...,
Describe four steps in gene expre...,
What is an advantage of regulatin...
34
cards
LEC22: Chromatin and Gene Structure
What are the molecules that make ...,
What is teh direction of nucleic ...,
Name the types of sequences that ...
51
cards
LQTS
What is vm of the heart,
2
cards
LEC23: Basal & Regulated Transcription
What are the phases of transcription,
What is the core promoter,
How are upstream ntds designated ...
46
cards
LEC24: An Example of Regulated Txn & mRNA Processing I
What is normal hemaglobin structure,
Fetal vs adult globin chains,
Where are alpha and beta globin g...
25
cards
LEC25: mRNA Processing II
What are the parts of pre mrna pr...,
What is the structure of an intron,
What happens if splicing is incor...
31
cards
LEC26: Translation Machinery & Mechanism I
What is translation,
What is a trna,
What holds together the trna stru...
28
cards
LEC27: Translation Mechanism II & Regulation
What are the steps of translation...,
What is dwell time its effect,
What is eef1a what does it do
30
cards
LEC28: Nucleic Acid Analysis
What is a dna oligonucleotide,
What is nucleic acid synthesiss p...,
Wht is the purpose of northern bl...
32
cards
LEC29: DNA Replication
Where does dna replicaton begin,
What signals its time to replicat...,
During which phase of cell cycle ...
32
cards
LEC30: DNA Repair
What is the estimated daily incid...,
What are the greatest contributor...,
Why would a replication error occ...
30
cards
LEC31: Recombination, Transposition, Genomic Repeat Sequences
What does homology dependent dna ...,
What might might cause dna to com...,
What is homology based recombination
44
cards
LEC32: Protein Quality Control in the Cell
How is aggregation of newly made ...,
How do molecular chaperones promo...,
What is mechanism by which misfol...
46
cards
LEC33, 34: The Secretory Pathway & Endocytosis (Part A: Overview & Part B: The ER)
Part A: Overview of secretory pathway and lysosomal/endosomal system
Part B: The ER
43
cards
LEC34: The Secretory Pathway and Endocytosis (Part C: The Golgi Apparatus & Pathways for Protein Secretion)
How do proteins that fold in er m...,
What is the structure of the golg...,
What happens to proteins as they ...
21
cards
LEC35: Secretory Pathway and Endocytosis (Part D: Endocytosis, Part E: Mechanisms of Vesicular Transport)
Basic function of smooth er rough...,
Regulated vs constituitive secret...,
What is endocytosis
35
cards
LEC36: Transport into Mitochondria, Peroxisomes, & the Nucleus
What of proteins go through the s...,
What of liver volume do mitochond...,
Size of mitochondria
62
cards
LEC39: Mendelian Inheritance
What may changes in dna sequence ...,
What is snv,
What is snp
75
cards
LEC40: Inborn Errors of Development: Genetics of Congenital Anomalies
Key developmental pathways in inb...,
Dysmorphology,
Anomaly
61
cards
LEC41: Mitosis and Meiosis
What are the steps of mitosis as ...,
What do microtubules and actin fi...,
In what important way does meiosi...
37
cards
LEC42: Inborn Errors of Development: Chromosomes and Cytogenetics
Cytogenetics,
What proportion of 1st trimester ...,
What of cardiac defects do chromo...
74
cards
LEC43: Intro to Genomics
What does every human cell contain,
When are chromosmoes visualizable,
What was first genome screen tech...
40
cards
LEC44: Non-Mendelian Inheritance
Epigenetics,
Are epigenetic changes heritable ...,
How does epigenetic change occur
40
cards
LEC45: Pharmacogenetics and Pharmacogenomics
What is personalized medicine,
Pharmacogenetics phamacogenomics,
What benefit might personalized m...
28
cards
LEC46: Genetics of Complex Disease
What does the spectrum of disease...,
Difference between mendelian mode...,
How can one determine heritability
32
cards
LEC47: Population Genetics
Population genetics is,
Subpopulation,
What marks evolution of a populat...
34
cards
LEC48: Applications of Next Gen Sequencing
How does sanger sequencing work,
How does next gen dna sequencing ...,
What is massively parallel sequen...
30
cards
LEC49: Intro to Cell Cycle
Techniques for measuring cell pro...,
Purpose of creating mitotic index,
Why how does mitotic index count ...
45
cards
LEC50: Cell Cycle Progression and Checkpoints
What determines entry into s phase,
What are the 3 kinds of signaling...,
What upregulates cyclin d
49
cards
LEC37: Cytoskeleton
Cytoskeleton function,
Filament types of cytoskeleton,
Gross structure of cytoskeleton f...
39
cards
LEC38: Cells in Tissues: Junctions, Adhesion, and Extracellular Matrix
What is epithelia,
Are epithalial cells polarized,
Kinds of cells in body
44
cards
LEC51: Properties of Cancer Cells; Senescence
Benign vs malignant,
Primary cells,
Immortalized cells
26
cards
LEC52: Oncogenes
Who first proposed oncogene notion,
Definition of cancer re oncogenes,
What is rous sarcoma virus
43
cards
LEC53: Tumor Suppressors
What experimentally suggests tumo...,
What about inherited syndromes te...,
What are examples of inherited sy...
32
cards
LEC54: Cancer Pathways and Tumor Biology
What are the components of the rb...,
How are rb pathway targets altere...,
What mutations happen to p16
56
cards
LEC55: Apoptosis
What changes does cell undergo fo...,
What is apoptosis what happens to...,
What assays measure cellular apop...
44
cards
LEC56: Cancer Genetics and Genomics
What are the hallmarks of cancer,
What are emerging hallmarks of ca...,
What are the genetic points of vi...
33
cards
LEC57: Cell Differentiation, Stem Cells, and Reprogramming
What is a differentiated cell,
What is the idea of progressive a...,
How does combinatorial gene contr...
45
cards
METABOLISM SYLLABUS 1: Intro to Metabolism & to Metabolic Regulation by Insulin & Glucagon
Metabolism,
What are the functions of metabolism,
Catabolism vs anabolism
50
cards
METABOLISM SYLLABUS 2: Glycolysis: functions, pathway, energetics, regulation
Function of glycolysis,
How do rbc get energy,
To what organs is glycolysis the ...
40
cards
METABOLISM SYLLABUS 3: Fates of Pyruvate
What can happen to pryuvate from ...,
What does ldh reaction catalyze,
Where does ldh reaction occur
26
cards
METABOLISM SYLLABUS 4: TCA Cycle (aka Krebs Citric Acid Cycle)
Where does tca cycle occur,
What is the net reaction of the t...,
How many atp are yielded per mole...
26
cards
SYLLABUS 5: Mitochondrial Carriers and Substrate Shuttles: the Pentose Phosphate Pathway
Purpose of mitochondrial carriers,
Carrier 1 action,
Carrier 2 action
37
cards
SYLLABUS 6: Glycogen Metabolism
What is glycogen,
What does branching do for glycogen,
Under what conditions is glycogen...
37
cards
SYLLABUS 7: Gluconeogenesis
What organs synthesize glucose,
Under what conditions is glucose ...,
Primary substrates for gluconeoge...
30
cards
SYLLABUS 8: Fatty acid oxidation & ketone body production
What does oxidation of fatty acid...,
Where are fatty acids important,
Where does out dietary fat come from
38
cards
SYLLABUS 9: Fatty acid biosynthesis
When are fatty acids synthesized,
Where does fatty acid biosynthesi...,
What happens to excess fatty acid...
22
cards
SYLLABUS 10: Cholesterol Metabolism
What are cholesterols main functions,
Cholesterol fxn in liver,
Cholesterol fxn in endocrine tissues
27
cards
METABOLISM QUIZ 1 Review Questions
Epinephrine causes increased glyc...,
What would addition of arsenic do...,
A pyruvate kinase deficiency of t...
24
cards
SYLLABUS 11-12: Bioenergetics
What does oxidative phosphorylati...,
Where does oxidative metabolism t...,
Function and location of the elec...
59
cards
SYLLABUS 13: Reactive Oxygen Intermediates in Biology & Medicine
Free radical is,
Charge of free radicals,
Why is molecular oxygen important
76
cards
SYLLABUS 14: Amino Acid Metabolism - General Introduction
Recommended amt of protein in the...,
Where does protein digestion occur,
Essential vs non essential amino ...
32
cards
SYLLABUS 15: Metabolism of the Alpha Amino Group of Amino Acids and the Urea Cycle
What happens to excess aa,
What happens to alpha amino group...,
Where does most aa metabolism occur
37
cards
SYLLABUS 16: Methylation Reactions in Biological Systems: Vitamin B12 Metabolism
Is met essential or nonessential aa,
Why is met important,
What is sam
38
cards
SYLLABUS 17: Metabolism of 1C Fragments, Folic Acid Biochemistry
What is the active form of folic ...,
How does thf function,
What are the carbon atoms thf use...
27
cards
SYLLABUS 18: Nucleotide Metabolism
Functions of purines and pyrimidines,
Difference between a nucleoside a...,
How does purine synthesis begin
32
cards
SYLLABUS 19: Nucleotide & Deoxynucleotide Metabolism
What is the first pyrimidine made,
What is cps ii,
First step of pyrimidine synthesis
35
cards
SYLLABUS 20: Amino Acid Catabolism
When does amino acid catabolism o...,
How are aa removed from the body,
What tissues degrade excess aa
50
cards
SYLLABUS 21: Amino Acid Anabolism
Where does non essential aa synth...,
Anabolic synthesis of glutamate,
Anabolic synthesis of glutamine
35
cards
SYLLABUS 22: Amino Acids as Precursors to Molecules (other than ntds and catecholamines)
Functions of aa,
What is glutahione,
How is glutathione synthesized
44
cards
SYLLABUS 23: Metabolism of Heme
Function of heme,
Wheres heme synthesized,
Where does heme synthesis occur
44
cards
Inborn Errors of Metabolism
Defn of inborn errors of metabolism,
What occurs to cause an iem,
Principles of treatment of iem
41
cards
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