This class was created by Brainscape user Giovanna Zampierollo. Visit their profile to learn more about the creator.
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Decks in this class (30)
Hematopoietic Stem Cells And Hematopoiesis
Two fundamental properties of hom...,
Sources of hematopoietic stem cells,
Properties of hematopoietic stem ...
28
cards
aplastic anemia & bone marrow failure states
Aplastic anemia,
Cause of congenital aplastic anem...,
Cause of congenital aplastic anem...
14
cards
hypoproliferative
Erythropoiesis in bone marrow doe...,
In the most simplest term anemia ...,
Of red cells in a ul of blood
60
cards
white blood cells
The most prominent white blood cell,
Lifespan of neutrophils,
One step prior to mature neutroph...
26
cards
coagulation cascade
Primary hemostasis 3,
Vwf and collagen,
Shape change
26
cards
platelets
Anucleate cells derived from mega...,
Platelets 1 production2 nl count3...,
Alpha granules 1 fibrinogen2 thro...
48
cards
thrombosis and fibrinolysis
Thrombosis pathologic event 3,
Virchows triad,
Fibrinogen to fibrin and feedback...
24
cards
bleeding disorders
Interpretation of mixing studies ...,
Interpretation of mixing studies ...,
Quantitates factor activity levels
36
cards
hyperproliferative
Increased rbc destruction results...,
Are we going to see an increased ...,
Depends on severity rate of hemol...
27
cards
thalassemias
Alpha globin cluster is on chromo...,
The two alpha a genes are highly ...,
Most globin synthesis occurs from
36
cards
sickle cell anemia
Sickle cell disease1 inheritance2...,
Variant hemoglobin meaning the mu...,
Heterozygous inheritance or sickl...
51
cards
Blood blank transfusion
Whole blood is filtered to remove...,
What are a few of the transmissib...,
Platelets require constant agitat...
58
cards
laboratory diagnosis
Example of a mass screening,
Example of a screening for asympt...,
Example of a screening for sympto...
51
cards
intro to hematologic malignancies
Derived from cells in the bone ma...,
Neoplastic transformation occurs ...,
Acute leukemia arises from
30
cards
anticoagulation: pharm
Three major natural anticoagulant...,
Antithrombin at inhibits coagulation,
What accelerates at inhibitor fun...
38
cards
acute leukemia
There are 2 types of acute leukemia,
Aml epidemiology1 incidence2 prev...,
All epidemiology 1 incidence2 pre...
61
cards
pharmacology overview
Log kill hypothesis 1 doubling ti...,
Goldie coldman hypothesis 1 takes...,
Types of treatment 5
51
cards
alkylating agents and hormonal agents
Mechanism pf action for alkylatin...,
As a class alkylating agents caus...,
Forms a reactive electrophile tha...
37
cards
antimetabolites
Anti metabolites are generally mo...,
Anti metabolites 4,
Methotrexate mtx is a _______ ant...
28
cards
antibiotics plant alkaloids
Doxorubicin,
Irinotecan topotecan,
Vincristine vinblastine vinorelbine
43
cards
Biologics and targeted therapy
Monoclonal antibody production re...,
Kohler and milstein produced the ...,
Mab
41
cards
non-hodgkin lymphoma
Lymphoma,
Acute lymphocytic leukemia cells ...,
Present a period of vulnerability...
55
cards
Hodgkin's
The presenting signs and symptoms...,
Hodgkin s lymphoma makes up ____ ...,
The incidence of hl appears incre...
31
cards
CLL
Chronic lymphocytic leukemia cll ...,
The presenting symptoms of lympho...,
Cll is characterized by an over a...
42
cards
Plasma cell disorders
The ___________ encompass a spect...,
Plasma cell disorders 6,
Recall that an immunoglobulin mol...
54
cards
myelodysplastic syndromes
Mds a it is a __________ disease ...,
Bilogical features of mds 1 stem ...,
Approximately 90 of mds cases are...
19
cards
myeloproliferative neoplasms
Mpns is defined as unregulated ce...,
Two important tyrosine kinase mut...,
Positive philadelphia chromosome
32
cards
Hematopoietic stem cell transplantation
Hsct allows for reconstitution of...,
Hsct in some cases provides a gra...,
Stem cell sources 1 a largest res...
45
cards
Histo/path
47
cards
review
Where is the biopsy done on for a...,
Where is the biopsy done on for a...,
Clonal disorders of impaired diff...
75
cards
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