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rena luvr
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Decks in this class (56)
1- pharma general
Drugs,
What are biologic drugs and what ...,
What are small molecule drugs an ...
14
cards
2- states of drug production
What is the cost of developing a ...,
What is the typical project progr...,
How long does a new molecular ent...
14
cards
3- project initiation
What kind of assessments are made...,
What kind of market analysis is d...,
What kinds of drugs sell the most...
8
cards
4- discovery leads part I
What are the five different metho...,
What are the most common to least...,
What is high throughput screening...
29
cards
5- discovery leads part II
What is combinatorial chemistry w...,
What is the problem with combinat...,
Explain the general steps of doin...
16
cards
6- drug development
What are the five major goals tur...,
What are the three aspects of doc...,
What is a patent and what are the...
24
cards
7- clinical trials overview
What things are looked for in dru...,
What must the drug be made in acc...,
How much of the cost of the new d...
23
cards
8- bio targets I
What are proteins,
What are nucleic acids,
What are polysaccharides
26
cards
9- Protein structure I
What is the primary structure of ...,
How do you read a primary sequenc...,
What are 4 different types of sec...
16
cards
10- protein structure II
What are tertiary structures what...,
What are four examples of why ter...,
What are the three different attr...
13
cards
11- protein targets-enzyme
List the four different protein t...,
Explain the enzymes as protein ta...,
Explain the receptors as protein ...
15
cards
13- enzymes II
State the michaelis menten kineti...,
What is vmax,
Michaelis menten kinetics equatition
19
cards
14- receptors and drugs
How do messengers work,
Explain chemical messaging via bi...,
Explain chemical messaging via ca...
19
cards
15- sar part 1 drug binding
What are the 5 ways drugs produce...,
What are the 4 ways drugs bind to...,
What causes selectivity in the no...
14
cards
16- sar part 2 properties
What is potency what are the unit...,
Explain the four steps of sar to ...,
Explain what spr is
17
cards
17- sar part 3 lipinski
Explain when an acid is lipid sol...,
Explain when a base is lipid solu...,
Where do the drugs pass once in t...
19
cards
18- sar part 4 pKa
What are the percentages of of io...,
What controls water solubility,
Pka with acids
21
cards
19- sar part 5 metabolism
What is phase i of metabolic stab...,
What is phase ii of metabolic sta...,
Explain the example of cyp450 in ...
9
cards
20- sar part 6 molecular mods
What are the four steps of drug o...,
What are the seven techniques of ...,
What are isosteres
13
cards
assignment 1
List the following for phase i go...,
List the following for phase ii g...,
List the following for phase iivi...
26
cards
assignment 2
What are the 5 major classes of a...,
18 of the common amino acids have...,
Briefly explain what constitutes ...
21
cards
assignment 3
Describe electrostatics in terms ...,
Describe hydrogen bonds in terms ...,
Describe dipole dipole in terms o...
21
cards
21 - sulfa drugs
What are antibiotics,
What are the drugs targeted towar...,
What is the leading cause of deat...
16
cards
22 - penicillin and cross links
What percentages of antibiotics c...,
Explain alexander flemings discov...,
What did howard florey and ernst ...
15
cards
assignment 4
What is a classical isostere give...,
What is a non classical isostere ...,
Why was salvarsan 606 not a comme...
15
cards
23 - transpeptidase 2
Describe the serine protease acti...,
Describe the reaction of amide hy...,
Describe the reaction of amide hy...
12
cards
24 - penicillin design i
What is the functional part of th...,
Describe the mechanism and struct...,
What is b lactam carbonyl and why...
11
cards
25 - penicillin design ii
Describe how penicillin g is turn...,
What is dcc and what does it do,
What do transpeptidase mutations ...
17
cards
26 - clavulinic acid
What are cephalosporins when were...,
What are the advantages to cephal...,
What are the disadvantages of cep...
18
cards
27 - intro to viruses
What are most infectious diseases...,
What pathogen class includes only...,
What is the risk for class 1 path...
16
cards
28 - challenges to antiviral discovery
What are the two difficulties in ...,
Explain how the uniqueness of vir...,
Explain how the viral proteins bi...
18
cards
29 - viral life cycles and drug targets
What are the seven steps in the v...,
Describe the adsorption and penet...,
Why are adsorption and penetratio...
10
cards
30 - herpes i
What is herpes and what are the t...,
Where does herpes reside,
Describe hsv 1 including the symp...
23
cards
31 - herpes ii
Describe sta,
Explain the process of chain term...,
What does combining non natural b...
18
cards
32 - influenza
What is influenza describe its mu...,
How many influenza pandemics have...,
What are the three sub types of i...
32
cards
33 - hep C i
What is hepatitis c when was it d...,
Describe the structure of the hep...,
What was the 2020 nobel prize in ...
5
cards
34 - hepatitus C life cycle
What is important about the movem...,
What is the importance of complex...
2
cards
35 - hepatitus C ii
What is sofobuvir how does it go ...,
Describe how chain termination is...,
What is ledipasvir and how does i...
4
cards
36 - covid virus i
0
cards
37 - covid drugs
0
cards
38 - hiv la
0
cards
39 - hiv lla
0
cards
40 - lipitor i
0
cards
assignment 5
Describe the general structures o...,
What are the general difficulties...,
Describe the stages of a typical ...
15
cards
covid assignment
The coronavirus family has severa...,
What are the pre existing medical...,
The initial entry of the covid vi...
7
cards
41 - lipitor 2
Why were docs afraid of prescribi...,
What is four s study of simvastatin,
Describe statins complex structur...
14
cards
42- ulcers
Discuss the timeline of ulcer dru...,
Why are ulcers fatal and how many...,
How much was spent on antacids in...
21
cards
43- h2 antagonists
How many protonation sites does h...,
Explain the receptor site of hist...,
What happens when you change the ...
28
cards
44- proton pump
What is the proton pump,
What are parietal cells,
What is the difference between h2...
21
cards
45- insulin i intro and early purification
What are biologic drugs,
What is diabetes what can it caus...,
What is insulin and what does it ...
21
cards
46- insulin ii general chromatography
How does zn 2 promote crystalliza...,
Outline the development of chroma...,
How does extraction work
13
cards
47- insulin iii purification
How does ion exchange chromatogrp...,
How does sulfonic acid get ionize...,
What are the various types of resin
14
cards
48- insulin iv
0
cards
49- insulin v
0
cards
50- HGH I
What is hgh where is it and what ...,
What does hgh deficiency cause,
What is the earliest treatment fo...
16
cards
51- HGH II
0
cards
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