membranes Flashcards

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1
Q

is lipids and water non polar or polar?

A

lipids are no polar and water is polar

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2
Q

what is a micelle?

A

a spherical arrangement of phospholipids

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3
Q

hydrolysis meaning?

A

breaking something down/ apart using water/ because of the addition of h20

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4
Q

what is a condensation reaction?

A

when a bond is formed that is a condensation reaction. 2 molecules combine to form a large molecule and produce a smaller molecule such as H20 as a byproduct

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5
Q

how are phospholipid bilayers formed?

A

formed when they are placed in an aqueous environment

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6
Q

what are transmembrane’s?

A

transmembrane’s are proteins only within the phospholipid bilayer. they are within which is integral. there are proteins are attached which is peripheral.

they can also be permanent or temporary

gated transmembrane channels allow selected molecules through depending on conditions within the cell which determine whether they open or close.

there transmembrane Chanels allow substances to pass through in both directions. some are active carrier systems which use energy to transport.

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7
Q

what are the functions of transmembrane’s (proteins)?

A

allow for transport of substances that are not able to go (diffuse) through phospholipid bilayer themselves.

ionic, molecular and electron transport

They can be (carrier) which cahnegs shape during facilliated diffusion yet do open and close. or they can be channel which does not change shape during facillitated diffusion. Facillitated iffuiosn is stil passive)

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8
Q

what are glycoproteins ?

A

proteins which have carbohydrate groups attached to them. they allow cells to communicate with one another and are used for immunity.

proteins on the cell surface also act as receptors for incoming messages such as hormones. (proteins used for communication and transport)

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9
Q

describe and explain the fluid mosaic model of plasma membrane (cell membrane)?

A

phospholipid bilayer is not fixed structure/ not rigid/ flexible although the bilayer will always remain arranged in this configuration. Thus membranes can change shape for processes like phagocytosis. It also allows proteins to move latterly within he cell membrane.

fluid - specifically refers to the movement of phospholipids in the plane of the membrane

it is mosaic as it is made up of many macromolecules including glycoproteins, lipoproteins, cholesterol , transmembrane proteins and phospholipids.

mosaic refers to the random arrangement/ association of proteins different shapes and sixes within the membrane/ phospholipid bilayer

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10
Q

why is it important for cell membranes to have fluid mosaic model?

A

carry out function effectively

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11
Q

what Can affect fluidity of cell membrane ?

A

the ratio of saturated and unsaturated fatty acids determins fluidity. cholesterol helps the cell membrane remain correct fluidity. during warmer temperatures it provides structural support to prevent phospholipids from becoming too fluid. cholesterol enhances the permeability bilayer. more cholestrol makes the membrane stabalized and have a higher meltig point.

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12
Q

how many fatty acids are there in the fatty acid chain

A

two fatty acids in fatty acid chain which are hydrophobic

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13
Q

describe the structure of the plasma (cell membrane).

A

The structure of the cell is comprised of a phospholipid bilayer with the phosphate hydrophilic (polar) head pointing outwards and the 2 fatty acid chains
( hydrophobic/ non polar) directing inwards and a glycerol backbone. within the bilayer there are proteins called transmembrane (ionic, molecular, electron transport), these are integral and allow substances which cannot enter/ diffuse through the cell bilayer to enter they are either carrier or channel. In addition to this here are peripheral proteins attached to the outside and slightly within the phospholipid bilayer. plus they have glycoproteins which are proteins with carbohydrate groups they allow for communication between cells. furthermore they contain cholesterol between the fatty acid chains of phospholipid bilayer.

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14
Q

what do proteins and transmembrane aid the movement of?

A

allow the movement/ absorption of large/ charged/ polar molecules. such as water, glucose/ water soluble vitamins.

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15
Q

what are the meanings of
Solute
Solvent
Solution
HypErtonic
HypOtonic
Isotonic

A

solute - substance which is dissolved
solvent - liquid in which the solute is dissolved

solution- solvent with solute dissolved in it

Hypertonic- if the solute concentration is higher in solution than inside cell - in relation to solution

Hypotonic- solute conecntartion is lower outside cell that inside - this in relation to solution

isotonic- concentration of solute inside and outside cell is the same

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16
Q

what is osmosis

A

net movement of water molecules from a solution with a lower concentration of a solute to a higher concentration of a solute through a partially permeable membrane.

17
Q

what is active transport

A

Active transport is the movement of molecules or ions across a membrane via a carrier protein against their concentration gradient using energy supplied by ATP. Active transport always uses a carrier protein.

18
Q

what are the two main examples of bulk transport and definitions ?

A

Endocytosis substances into cell.

Exocytosis substances out of cell.

19
Q

what is the purpose of Endo and Exocytosis ?

A

ions and some molecules are too large to be transported across membrane into cell. eg proteins or bacteria. Instead they are packages in vesicles ( small membrane bound sacks) which fuse together with the membrane

20
Q

is Bulk transport active or passive?

A

Active and is provided with energy from ATP

21
Q

describe the process of Endocytosis?

A

Endocytosis transports large molecules or ions into cell by the cell membrane caving inwards to form a cavity around the large molecules or ions (polar| hydrophilic molecules), this is called invagination

Particles are then encircled to form a vesicle which moves into cell.

22
Q

Why can’t Ions go through transmembrane proteins ?

A

Charged atoms or molecules of any size cannot cross the cell membrane via simple diffusion as the charges are repelled by the hydrophobic tails in the interior of the phospholipid bilayer. there for Betty need to be transported in a vesicle.

23
Q

what is the difference between a micelle and a vesicle

A

a micelle is a spherical arrangement of phospholipids where as a vesicle is a spherical arrangement of a phospholipid bilayer with ions or molecules inside it.

24
Q

describe the process of Exocytosis?

A

Exits of proteins, hormones, certain enzymes etc.

At beginning portions found in Golgi apparatus. here portions are modified before secreted .Next vesicle containing containing substance buds of Golgi apparatus towards cell membrane, then fuse with cell membrane and protein is secreted.

25
Q

Does active transport:
require energy?
types of transport?
types of molecule?
importance?

A

It requires energy

Bulk (vesicular), exocytosis and endocytosis, phagocytosis, pinocytosis.

Ions, glucose, amino acids (any polar molecule)

Allows important polar molecules and ions to enter and exit cell cytoplasm.

26
Q

Does passive transport:
require energy?
Types of transport?
Types of molecule?
Importance?

A

Does not require energy

Osmosis, facilitated diffusion, simple diffusions.

oxygen, carbon dioxide, gases, water

important roles in homeostasis, movement of substances into and out of the cell, keep conditions within normal ranges inside the cell and the organism as a whole.

27
Q

draw the structure of an amino acid ?

A

glycine is the simplest amino acid. H side is amino group O side is acid group.

28
Q

what is the only thing that varies in an amino acid ?

A

only the R group on an amino acid varies due to there being 20 different amino acids there are 20 different R groups.

29
Q

what does a condensation and hydrolysis reaction form in terms of amino acids ?

A

a condensation reaction forms a dipeptide which is 2 amino acids would together and the water has been created as a byproduct ( It has come out of amino acid to form dipeptide )

when water is then added back to the dipeptide which is hydrolysis the dipeptide turns into 2 separate amino acids.

30
Q

what is a dipeptide and a polypeptide?

A

A dipeptide is 2 amino acids bound together and then water is produce as a byproduct

a polypeptide is multiple amino acids bound together.

31
Q

what is the formation process of proteins.

A

amino acids (monomers)- dipeptides -polypeptides - proteins (polymers)

32
Q

draw a condensation reaction and a hydrolysis reaction of an amino acid.

A
33
Q

what are the structures, properties, functions and examples of Fibrous proteins ?

A

structure: Remain as long chains, several amino acids cross linked together roe extra strength. Only reach secondary structure. Insoluble ( inward facing hydrophilic R groups)

Function: Not very reactive, useful when support and strength is needed .eg. muscle contraction proteins.

examples: Collagen (3 chains with crosslinks). very strong and rigid. used in connective tissue eg skin, bone, muscle.

34
Q

What are the structure, properties and examples of globular proteins?

A

structure: Polypeptide chain folded into compact spherical shape

properties: Soluble ( outward facing hydrophilic R groups)
Often used in metabolic reactions, easily denatured, useful when shape is important eg enzymes

example: Haemoglobin; four polypeptide chains bound to the prosthetic group (heam) which binds to oxygen.

35
Q
A

primary:
peptide bond
is the sequence of amino acids

secondary:
hydrogen bond
between amino + acid groups cause polypeptide to twist into a coil called alpha helix and beta sheets

Tertiary
Disulphide/ ionic/ hydrogen/ hydrophobic types of bond
super coiling across to create 3d shape hydrophilic

Quaternary
covalent bonds
protein is made up of more than one peptide linked together eg haemoglobin and collagen

36
Q

clarification on what can go through transmembrane and what processes

A

channel and carrie transmembrane allow for facilitated diffusion

channel can only transport small, hydrophobic/ non polar (not charged), or polar but uncharge molecules

only carrier proteins can also for active transport