Enolate predict product Flashcards
1
Q
how to recognize self aldol
A
NaOH (base)
H20
0 degrees
2
Q
how to recognize self aldol condensation
A
NaOH (base)
H20
Heat
3
Q
how to recognize crossed aldol addition T1
A
- both compounds have alpha hydrogen
THF (base)
acid
4
Q
how to recognize cross aldol addition T2
A
- only 1 has alpha hydrogen
THF base
acid
5
Q
what to do for self aldol
A
- align eachother
- turn one R group down
- get rid of H on other and turn into OH
6
Q
what to do for self aldol condensation
A
same as self aldol but
- get rid of OH entirely
- add pi bond in alpha beta position
7
Q
what to do for crossed aldol addition (T1)
A
- keep aldehyde, turn down R
- break open O on ketone
8
Q
what to do for crossed aldol addition (T2)
A
- keep entire aldehyde (or species w alpha H), just turn down R group
- add together, turn O on other compound in to OH
9
Q
claisen condensation
A
- just add ketone to ester
10
Q
acetoacetic ester synthesis
A
keep beginning ester, delete everything else
- ch3,
