yuck Flashcards
what are LFA-1, VLA-4
integrins for adhesion
role of CD2 + CD5
double negative commit to T-cell lineage
what is NF-AT needed for
IL-2 gene transcription
what do Tfh cells do
stimulate antibody production by B cells
class switching and affinity maturation
what do Th17 cells do
stimulate neutrophil response to bacteria and fungi
- secretes IL-17 and IL-22
what do Th1 cells do
express INF-y and IL-2
control bacteria that grow in macrophage
what is the role of CD40/CD40L
activate macrophages
activate B cells to produce antibodies
role of IL-2
T-cells —> effector
role of CD69
Keeps stimulated T cells in the lymph node
binds S1P
Role of CTLA-4
binds B7 on APC to limit T-cell proliferation
blocks CD28 signaling
role of IL-4
stimulates Th2 cells
IL-5
activates eosinophile
IL-13, IL-4
increase mucus secretion
IL-17
recruitment of neutrophils and stimulates production of antimicrobial peptides
IL-22
epithelial integrity
