Week 1 formative Flashcards
what disease causes blistering of the back of the hands and excess hair growth (eg on the face)?
PCT (porphyria cutaenea tarda)
what cells are responsible for vitamin D metabolism?
keratinocytes
what cells are responsible for energy storage?
subcutaneous fat
what cells are responsible for epidermal proliferation?
basal cells
what cell release inflammatory mediators in the skin?
mast cells
Langerhans are antigen presenting cells
what is a main component of a virulent strain of MRSA which causes necrotising fasciitis?
PVL
Panton Valentine Leukocidin
Apocrine glands vs Eccrine glands?
apocrine = scent glands eccrine = moisten hands and feet for grip
what is found in the dermis?
fibroblasts
ground substance
lymphatics
which enzyme is deficient in acute intermittent porphyria
Porphobilinogin Deaminase (PBG Deaminase) 3rd enzyme in production of haem
where are Odland bodies found?
granular layer
where are metabolically active cuboidal cells found?
basal layer
where are polyhedral cells with lots of desmosomes found?
prickle cell layer
what is required to maintain good circulation in the lower limb?
venous valves
muscle pump
pulse pressure
how much do finger nails grow per day?
0.1mm
painful and slightly red skin on sun exposure but normal on clinical examination?
erythropoetic protoporphyria