W4: Type C - E adverse drug reaction Flashcards
Type C adverse reactions are due to _________.
chronic responses related to long term drug use , (cumulative toxic effect)
An example of type C adverse reaction is _________ where the kidney is damaged due to long term analgesic medication.
Analgesic nephropathy
Type D adverse reaction are _____, happens many years after treatment
delayed
An example of type D adverse reaction is ______ in patients treated with alkylating agents like cyclophosphamide (chemoptherapy drug)
development of secondary cancer
Type E adverse reaction is known as ______ , happens when drug treatment is terminated suddenly
withdrawal reactions = undesired effects after stopping therapy
Example of type E adverse reaction is _______,
withdrawal effect due to termination on anticonvulsant therapy
Severity of the type E adverse reaction depends on the ___________
level of dependency
Drug abuse cases might lead to ________ adverse reaction
type E adverse reaction