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Physiology > Vitamin B12 > Flashcards

Vitamin B12 Flashcards

1
Q

What are the stages of vitamin B12 absorption after eating it?

A
  1. Bound to salivary TCN1 (protects it from stomach acid)
  2. Complexed by haptocorrin in stomach
  3. Haptocorrin is degraded by pancreatic enzymes
  4. Bound to intrinsic factor (from the stomach)
  5. Absorbed in the intestines across the enterocyte by cubilin receptors
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2
Q

What are the main dietary sources of vitamin B12?

A 
Fortified cereals
Liver
Kidney
Fish
Dairy foods
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3
Q

How long does B12 depletion take?

A

Approximately 3 years, we have a large store of B12 distributed amongst many places in the body

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Physiology (20 decks)

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