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Path: Virology > Virus Structure > Flashcards

Virus Structure Flashcards

1
Q

What is a capsid?

A

Protein shell

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2
Q

Function of capsid?

A

1) protects nucleic acid from e-cellular env

2) delivers virus genome from one susceptible cell to another

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3
Q

What are capsomers?

A

Repeating protein subunits making up a capsid

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4
Q

Two types of capsomer symmetry?

A

Helical

Icosahedral

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5
Q

How may a virus acquire a lipid envelope?

A

From host cell in which virion produced, often budding nucelocapsid through plasma membrane

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6
Q

What does monopartite mean?

A

Single nucleic acid molecule (majority of cases)

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7
Q

Which virus cannot be titrated by plaque assay?

A

Hep B

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8
Q

What type of genetic material do papoviruses contain?

A

ds-DNA

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9
Q

Example of virus with a ds-RNA genome?

A

Reoviruses e.g human rotavirus

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10
Q

What type of genome does the influenza virus contain?

A

Negative strand RNA

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11
Q

What is the nucleocapsid?

A

Capsid and genome

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12
Q

Nomenclature: what are structural proteins?

A

Those found in the virion

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13
Q

Which poxvirus causes smallpox?

A

Variola virus

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14
Q

What is a virion?

A

Simplest virus particle composed of genome and capsid

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15
Q

Give four families dsDNA viruses?

A

1) Herpesviruses
2) Poxviruses
3) Papovavirus
4) Adenovirus

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16
Q

Example of ssDNA virus?

A

Human parvovirus

17
Q

Give 4 families of positive ssRNA viruses

A

1) Picornaviridae
2) Caliciviridae
3) Togaviridae & Flaviviridae
4) Coronaviridae

18
Q

Which virus causes winter vomiting disease?

A

Norovirus (Caliciviridae)

19
Q

Which family of viruses does rhinovirus belong to?

A

Picornaviridae

20
Q

Give 3 families of negative ssRNA viruses?

A

1) Orthomyxoviridae
2) Paramyxoviridae
3) Rhabdoviridae

21
Q

Which family of viruses dies rabies virus belong to?

A

Rhabdoviridae

22
Q

What does hepatitis B cause?

A

Acute and chronic hepatitis

Primary liver cancer

Path: Virology (7 decks)

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