Uworld week 3-4 Flashcards
what are people with dementia with lewy body really sensitive to?
antipsychotic side effects
what class of antipsychotics should be avoided in those with lewy body dementia?
typical antipsychotics
what is treatment of agitation in PCP use?
benzos
what are two favorable side effects of buproprion?
stimulant activity and weight gain
what are people with narcissistic personality disorder focused on?
a need for praise and admiration
what are people with obsessive compulsive personality disorder focused on?
orderliness and control
what are four risk factors for somatic symptom disordeR?
low SES
female
chronic illness
childhood neglect and rape
what is negativism in catatonia?
resistance to instructions and movement
how does movement change in catatonia?
either immobile or excessive purposeless activity
what is treatment of catatonia?
benzodiazepines
what can catatonic patients do with their speech?
echolalia
what is the treatment for restless leg syndrome?
dopamine agonists…like pramipexole
aside from pramipexole, what else can be used for restless leg syndrome?
gabapentin
what do you try before meds for restless leg syndrome?
supportive measures…heating pad and exercise
what are signs of benzo withdrawal?
tremulousness, tachycardic, high BP, hallucinations
PTSD most increases risk for what?
depression and suicide
what are synthetic cathinones?
bath salts..in family of amphetamines
what are signs of synthetic cathinone intoxication?
agitation, combativeness, psychosis, delirium, and rarely seizures
what is abnormal about cathinone intoxication?
can last up to a week
what is RBD?
rapid eye movement sleep disorder
what happens during RBD?
normally in REM sleep you have muscle atonia, but brainstem doesnt do this in RBD and patients start to enact their dreams
when is it more likely for RBD to occur?
in the morning hours when REM sleep is occurring more
will patients with RBD recall movements or dreams?
will recall dream but not movement
3 SEs of methylphenidate
weight loss, loss of appetite and insomnia
what should the first step in management of a patient with postpartum psychosis be?
immediate hospitalization to rule out infanticide
what is rx of postpartum psychosis?
antipsychotics and treat underlying mood disorder
what are the symptoms of Dhat syndrome?
fatigue, weight loss and concern about losing semen during urination
where is Dhat syndrome found?
in southeast asia
what is first line treatment for depression with psychotic features?
antipsychotic and antidepressant
what can develop in kidney with NMS?
AKI…
what labs are abnormal in NMS?
leukocytosis, high CK, high creatinine and BUn
what are the three main early side effects of SSRIs?
HA, nausea and insomnia
what can happen to patients with akithisia who are made to sit still?
they can become severely agitated
what is the MOA of welbutryin?
NE and dopamine uptake inhibitor
what psych medication is most commonly associated with hepatotoxicity?
valproate
what two antipsychotics can be used in treatment of acute depression of bipolar disorder?
quetiapine and lurasidone
what psych disease is an ovarian tumor associated with?
NMDA receptor autoimmune encephalitis
describe the progression of NMDA receptor autoimmune encephalitis
flu like illness then changes in psych and physical health
what are the symptoms of NMDA receptor autoimmune encephalitis ?
psych issues then autonomic instability then rigidity hyperreflexive and seizures
two locations copper deposits in wilson disease
basal ganglia and cornea
what are the psychiatric symptoms of wilson disease
parkinsonism, psychosis, tremor, personality changes
when is RLS often worse?
at night
what helps RLS?
moving around
what lab is often abnormal in those with RLS?
low iron
name some medical causes of RLS?
diabetes, pregnancy, MS, parkinsons, uremia
how long must feelings of gender dysphoria last for diagnosis?
6 mos
how long must specific phobia last for diagnosis?
6 mos