UTI Flashcards
IGA Nephropathy BERGER
IgA complex deposition causing glomerulonephritis
IgA-Mucus in GI. Deposit lead to inflammation
Pop.- young adults, M
S/S- gross hematuria (bright red), URI, ILI, GI sx
TX- NONE. Resolves on own
Nephrotic Sydrome
Inc protein spilling/permeable w/in Glomerolus
Lipids, protein-normally too large, but cells open to filtrate, tubules keep in side lumen, excreted
Albumin- small gets resorbed, but gets filtered, not resorbed to blood, out in urine. Most abundant
RISK of infxn, d/t antibodies spilled/proteins
POP- kids (prime), adults (2nd to dz)
S/S- proteinuria, lipiduria, hypoalbuminenmia, edema hyperlipidemia. Mineral, protein, electroyte defincines
Salt/water rention
Minmal Change DZ
Def- loss of podyctes 2-6y peak. Absence of GM microscopic damage
S/S- h/o URI, allergy, immune
Focal segmental sclerosis
Focal scarring, Idipathic
S/S- hyposxia, SCD, HIV, HTN, reduced renal FX
Risk- advance to ESRD
Glomerulonephritis Injury
gm or renal tube-MC cause of renal failure in US.
SLE, DM
Antibody or complex sticks to membrane. Or overreact
Complement deposit w AB, which activates inflam
Alters permeability, membrane normally neg charge, turn positive charges on membrane.
Proteins and RBC pass freely into tubule bc of neg. charge themself
Immune system attacks d/t trigge
Scarring reduces GFR- filtration dependent on BF
forms less filtrate, dec urine
Findings RBC cast- membrane changed to neg charged Dec GFR-inc BUN Dec Urine HTN
Acute Cystiis. UTI
inoculation of e.coli, gram +. Asc to UT
S/s- irrative voiding, frequency, urgency, suprapubic discomforr
Prostatitis
Gram - rods (e.coli), pseudos, occ enterocci
Infected urine into prostate
S/S- fever, perineal pain, obstrutive sx. ASX for awhile
PE- no acute findings
UA- normal, INc Leukocytes
Epididymitis
<40y CT/NG cause
>40y nonSTI cause relaed to UTI/Prostatic
S/S- sperm cord radiates to Flank. Fever, scortal swelling
Prostadynia
Sx of voiding dfx, and pelvic floor dysfunction w/o infect or inflam. Similar to prostattis
DX- Clean UA, urodynamic test
Interstitial cystis
Pain w/ bladder filling, relief with emptying. Not single disorder,
Some abnormal protein
Sx- dysuria and frequency,
BPH
obstructive, irratitive voiding
enlarged on DRE
S/s- no UTI, stricture, malignancy
Metabolic Acidosis
Dec pH^
Dec. CO2*
Dec. HCO3*
N-pO2
Deficit in HCO3
S/S- inc. RR, RF- BUN/CR inc. growth stop, anorexia, wt. loss, weak, lack of enthusiasm
Correction
Inc. ventilation, blow off CO2. limit the bicarb reacton to dissocaiton.
Metabolic Alkalosis
Inc. pH^
Inc. CO2*
Inc. HCO3* >29
N-PO2
S/S- ASX or volume depletion (vomiting or Na loss)or hypokalemia
Neuro sx, HYPOventaliion (inc CO2 correct w/ more acide)
Sever- RDS, CV, Seizures, coma
Respiratory Alkalosis
Inc. pH^
Dec. CO2*
Dec. HCO3*
Dec.pO2
Respiratory Acidosis
Dec pH^
Inc. CO2*
Inc. HCO3*
dec.pO2