Urinary Drugs Flashcards

1
Q

Monurol

A

Antibiotic
Tx UTI, Cystitis
One dose
Pregnant women
Kills ESBL
GI s/e

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2
Q

Nitrofurantoin

A

Macrobid, Macrodantin
Antibiotic
Tx Chronic UTI, Cystitis
Avoid alkaline ash juices like orange and grapefruit

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3
Q

Trimethoprim

A

Primsol
Antibiotic
Tx UTI, Cystitis
Short term use
SE: Muscle cramps, swelling, dizziness

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4
Q

Trimethoprim/sulfamethoxazole

A

Bactrim, Septra
Antibiotic
Tx UTI, Cystitis
Blocks folic acid production
Take with water and on empty stomach
Caution: renal impairment

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5
Q

Fluconazole

A

Diflucan
Antifungal
Tx yeast infxn when taken with antibiotics

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6
Q

Methenamine

A

Hiprex
Urine Acidifier
Take with food and water
Avoid alkaline foods: milk, citrus, antacids

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7
Q

Methylene Blue

A

Urolene Blue
Urine Acidifier
Take with food and water
Avoid alkaline foods: milk, citrus, antacids

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8
Q

Ciprofloxacin

A

Cipro
Fluoroquinolones
Tx Cystitis
Interfere with DNA enzymes for cell reproduction
Liver toxic

Black Box: tendon rupture, CNS effects, peripheral neuropathy

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9
Q

Levofloxacin

A

Levaquin
Fluoroquinolones
Tx Cystitis
Interfere with DNA enzymes for cell reproduction
Liver toxic

Black Box: tendon rupture, CNS effects, peripheral neuropathy

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10
Q

Moxifloxacin

A

Avelox
Fluoroquinolones
Tx Cystitis
Interfere with DNA enzymes for cell reproduction
Liver toxic

Black Box: tendon rupture, CNS effects, peripheral neuropathy

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11
Q

Phenazopyridine

A

Pyridium
UT Analgesic
Tx: burning, urgency, frequency, pain, discomfort AFTER SURGERY, trauma or infection.
Affects UA results!
SE: reddish-orange urine, rash, HA, GI upset (take with meals)
Limits use to <2 days

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12
Q

Darifenacin

A

Enablex
Antispasmodic (anticholinergic)

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13
Q

Fesoterodine

A

Toviaz

Antispasmodic (anticholinergic)

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14
Q

Oxybutynin

A

Ditropan

Antispasmodic (anticholinergic)

Tx urge incontinence & cystitis

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15
Q

Solifenacin

A

Vesicare

Antispasmodic (anticholinergic)

Tx urge incontinence & cystitis

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16
Q

Tolterodine

A

Detrol

Antispasmodic (anticholinergic)

Tx urge incontinence & cystitis

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17
Q

Trospium

A

Sanctura

Antispasmodic (anticholinergic)

18
Q

Pentosan polysulfate sodium

A

Elmiron

Tx: Interstitial Cystitis
Bladder protectant

19
Q

Meds to Tx Urge Incontinence

A

Oxybutynin (Ditropan)
Solifenacin (Vesicare)
Tolterodine (Detrol)

Do NOT chew or crush these

Increase fluid intake

20
Q

Bethanechol chloride

A

Cholinergic Agonist

Tx Urinary retention, Overflow incontinence

AE: Abd discomfort, salivation, N/V, sweating, flushing

21
Q

Doxazosin

A

Cardura

Alpha-Adrenergic Antagonist
Tx: BPH, HTN
Relaxes bladder via dilation of arterioles and veins

SE: OH, ED

22
Q

Tamsulosin

A

Flomax

Alpha-Adrenergic Antagonist
Tx: BPH
Relaxes bladder via dilation of arterioles and veins

SE: OH, ED

23
Q

Dutasteride

A

Avodart

5-Alpha-Reductase Inhibitors (5-ARI)
Tx: BPH
Shrinks prostate size by blocking testosterone production

SE: OH, teratogenic, ED, impotence, dizziness

WEAR GLOVES

24
Q

Finasteride

A

Proscar

5-Alpha-Reductase Inhibitors (5-ARI)
Tx: BPH
Shrinks prostate size by blocking testosterone production

Reduces hair loss

SE: OH, teratogenic, ED, impotence, dizziness

WEAR GLOVES

25
Q

Avoid meds that cause urinary retention for BPH pts:

A

Anti-cholinergics, anti-histamines, decongestants, anti-depressants or antipsychotics

26
Q

Leuprolide

A

Lupron

Hormone therapy (LHRH) agonist

Tx: Prostate cancer
Blocks testosterone secretion

SE: Hot flashes, bone pain, ED

Often prescribed Bisphosphonates to prevent bone fractures

27
Q

Bicalutamide (Trade Name?)
Flutamide
Nalutamide

A

Casodex

Hormone therapy (anti-androgen drug)
Block testosterone
Tx: prostate cancer

SE: Liver toxic, gynecomastia

28
Q

Sildenafil

A

Viagra

Phosphodiesterase-5 (PDE5)

Avoid: HF pts, Nirates (OH)

29
Q

Tadalafil

A

Cialis

Phosphodiesterase-5 (PDE5)
Tx: ED

Avoid: HF pts, Nirates (OH)

30
Q

Vardenafil

A

Levitra

Phosphodiesterase-5 (PDE5)
Tx: ED

Avoid: HF pts, Nirates (OH)

31
Q

Meds to treat Pyelonephritis infection

A

Trimethoprim-sulfamethoxazole (Bactrim)
Piperacillin-tazobactam (Zosyn)
Ceftriaxone (Rocephin)
Ciprofloxacin (Cipro)
IV fluids

32
Q

Sodium polystyrene sulfonate

A

Kayexalate

Tx: hyperkalemia with CKD

33
Q

Sodium zirconium cylcosilicate

A

Lokelma

Tx: hyperkalemia with CKD

34
Q

Calcium acetate

A

Phoslo

Phosphate binder

Tx: hyperphosphatemia with CKD

Take on empty stomach!

35
Q

Sevelamer carbonate

A

Renagel

Tx: hyperphosphatemia with CKD

Take with meals!

36
Q

Erythropoiesis stimulating agents

A

Aranesp
Epogen
Mircera

Tx CKD anemia

Warning: Antibody Production!
Contraindicated with HTN

Best given IV for dialysis pts

37
Q

Meds to Tx neuropathy in CKD

A

Gabapentin (Neurontin)
Pregabalin (Lyrica)
Duloxetine (Cymbalta)
Amitriptyline (Elavil)

SE: Drowsiness (fall risk)

38
Q

Calcium carbonate

A

Calcitriol

Vit D analog
Tx: Hypocalcemia in CKD caused by renal osteodystrophy

39
Q

Azathioprine

A

Imuran

T & B-cell suppressors

Immunosuppressive drug therapy

SE: increased risk for infection, hepatotoxicity, G.I. distress, leukopenia

40
Q

Mycophenolic acid

A

Cellcept

T & B-cell suppressors

Immunosuppressive drug therapy

SE: increased risk for infection, hepatotoxicity, G.I. distress, leukopenia

41
Q

Cyclosporine

A

Sandimmune

T & B-cell suppressors

Immunosuppressive drug therapy

SE: increased risk for infection, hepatotoxicity, G.I. distress, leukopenia

42
Q

Tacrolimus

A

Prograf

T & B-cell suppressors

Immunosuppressive drug therapy

SE: increased risk for infection, hepatotoxicity, G.I. distress, leukopenia