Unit 5 Flashcards

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1
Q

What size are viruses

A

Smaller than bacteria
measured in nanometers

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2
Q

Capsid

A

a protein coat surrounding the Euclid acid core
attached to the outer layer
smaller units are called capsomeres

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3
Q

envelope

A

some viruses have these
the outer most layer
lipid bilayer sounding the capsids
viruses without these are called naked

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4
Q

virion

A

a completely assembled virus

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5
Q

spiked

A

glycoproteins
project from the outer later and attach the virions to receptors on the host cells
either hemoglutinin or neurominadase

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6
Q

protyolitic enzymes

A

breaks down capsid to release genetic material

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7
Q

multiplication of animal viruses

A
  1. attachment
  2. entry
  3. uncoating
  4. synthesis
  5. maturation
  6. release
  7. shedding
  8. transmission
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8
Q

attachment

A

spiked to receptor host cell

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9
Q

entry

A

fission - fusing of membranes to naked virus
endocytosis - meshed into the host cell

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10
Q

uncoating

A

breaks down capsid and releases genetic material

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11
Q

synthesis

A

replication transcription translation

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12
Q

maturation

A

virions are assembled

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13
Q

release

A

released to neighboring cells

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14
Q

How to detect viruses

A
  1. PCR techniques
  2. cell culture looking for CPE
  3. antigen detection with florescent antibodies
  4. EM
  5. detect antibodies to viruses
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15
Q

Prions

A

rouge proteins
9 animal diseases neurological
all fatal
pathogenesis: changes structures of normal proteins

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16
Q

viroids

A

single circular piece of RNA
does not code
causes plant diseases
for humans Hep D
interferes with translation

17
Q

Acute

A

disease develops rabidly with many symptoms

18
Q

chronic

A

long term continuous shedding of virus

19
Q

latent

A

cannot be detected

20
Q

Proto-oncogenes

A

are genes that can help cells replicate.

21
Q

Oncogenes

A

are gens that have the capability to change the cell into a tumor cell.

22
Q

Tumor

A

suppression genes are genes that encode for proteins that regulate cell division.

23
Q

Oncoviruses

A

are viruses that can cause cancer.