Understanding Renal Disease Flashcards
Functions of kidney
Acid base balance Erythropoietin production - makes RBCs Vit D3 activation Filtration Excretion BP control (RASS)
Dysuria
Pain when passing urine
Pre renal failure is related to…
Changes in CV integrity
Post renal failure is related to…
Obstructive
Inc pressure in bladder/urethra
How can you see a swollen renal pelvis in POST (obstructive) kidney disease?
Ultrasound
Feel for kidney
How can you diagnose PRE- renal disease?
BP (low)
Pulse (High)
Dehydration signs- lethargic
Test for INTRINSIC renal disease?
Urine dip stick
NephrItic syndrome findings
A clinical presentation- characterise conditions with these findings:
HaematurIa
ProteinurIa (mild)
Variably: hypertension, red GFR
NephrOtic syndrome findings
Proteinuria (large amount) - >3g in 24hrs
Hypoalbuminaemia
Peripheral oedema
Hyperlipidaemia
Variably: Haematuria, red GFR
Causes of nephrotic syndrome
Membranous GN
Minimal change GN
Lupus
Focal glomerulosclerosis
Membranous GN associations
Idiopathic Drugs (penicillamine) Hep B Malignancy Autoimmune diseases
Normal protein in urine
<150mg in 24 hrs
Proteinuria
> 3g in 24 hrs
Name some other conditions that lead to nephrotic syndrome
Amyloid
Diabetic nephropathy
Interstitial nephritis
Minimal change
Ig A nephropathy characteristics
Non visible Haematuria
Renal biopsy diagnosis
Extra renal manifestations- rash
