Tumor Suppresor Gene Flashcards

1
Q

Rb

A

Retinoblastoma

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2
Q

p53

A

Li-Fraumeni syndrome

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3
Q

APC

A
FAP
Colorectal cancer (adenoma-carcinoma sequence)
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4
Q

E-cadherin

A

Diffuse type gastric carcinoma

Invasive lobular breast carcinoma

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5
Q

PTEN

A

Breast, endometrium

Cowden syndrome

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6
Q

NF1

A

Neurofibromatosis 1

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7
Q

NF2

A

Neurofibromatosis 2

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8
Q

WT1

A

Wilms tumor

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9
Q

PTCH1

A

Gorlin syndrome

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10
Q

VHL

A

Von Hippel-Lindau disease

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