Trimethoprim Flashcards
1
Q
MOA
A
- Bactericidal
- Narrow spectrum
2
Q
Indication
A
- Lower UTI
- Co-trimoxazole contains trimethoprim + sulfamethoxazole: pneumocystitis jirovecil pneumonia (Causes SJS)
3
Q
Dose
A
200mg BD
4
Q
Side effect
A
Blood disorder
- Counsel: report signs of infection or blood disorder: sore throat, fever, mouth ulcers, bleeding
Hyperkalaemia
5
Q
Pregnancy
A
Teratogenic (antifolate)