Treponema Pallidum Flashcards
Family Treonemataceae
Consists of three genera
Leptospira
Borrelia
Treponema
Diseases caused by spirochetes
Leptospira : leptospirosis
Borrelia : lyme diseases
Treponema : Syphilis, bejel, yaws, pinta
Organisms of Genera Treponema are
All treponema pallidum
Sub species pollidum: veneral syphilis.
Sub species pertenue : yaws
Sub species endemicum : endemic syphilis
Treponema caroteum : pinta
TP general properties
Thin walled, GRAM POSITIVE.
Flexible rods, spiral shape
Axial filament
Obligate anaerobes
Fastidious bacteria
Grown in monley testes
Seen only in :
Dark field microscopy
Silver impregnation test
Immunoflourescence
Mode of transmission
Personal contact:
Sexual
Non sexual
Vertical transmission
Through blood transfusion
Hallmark of infection
Obliterative endarteritis
Plasma cell infiltration