transplants Flashcards

1
Q

what is considered when matching organs

A

HLA blood type

blood type

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2
Q

acute rejection

A

occurs days 3-14

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3
Q

chronic rejection

A

occurs after years

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4
Q

how is rejection detected?

A

ultrasound, if kidney is enlarged, t can indicate rejection, sometimes the kidney will need to be removed

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5
Q

kidney transplant patients are at a crazy high risk for what?

A

infection. (75% contract in infection in the first year post op)

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6
Q

two types of transplants that come from the pancreas

A

pancreas

islet cells

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7
Q

most common type of heart transplant

A

orthotopic: decreased AV valve regurgitation, dysrythmias, conduction abmnormalities

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8
Q

complications of a transplant

A
bleeding- leak at anastamosis 
DIC 
failure of other organ systems 
infection 
rejection
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9
Q

hyperacute rejection

A

graft fails minutes to hours after transplant
sometimes organ looks ischemic, and cyanotic in surgery, the organ is being attacked by the T-lymphocytes and donor organs

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10
Q

acute rejection

A

most common type of rejection
2 weeks to 2 years after surgery
most patients have an acute phase of rejection
prompt trx with is critical

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11
Q

when people go into rejection they normal encounter what?

A

the original S/s of failure

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12
Q

kidney rejection s/s

A
increased BUN/creatnine 
decreased urinary output 
increased blood pressure 
flu like illness 
low grade fever 
dependent edema 
uremic frost
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13
Q

liver rejection s/s

A
RUQ tenderness 
increased liver enzymes 
flu like symptoms 
itching and jaundice 
elevated LST/AST
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14
Q

pancreas rejection

A

decreased urine pH
decreased amylase
hyperglycemia (late sign) r/f DKA

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15
Q

lung transplant rejection

A

asymptomatic
fever, malaise, dyspnea
nonproductive cough
drop in pulse ox

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16
Q

heart rejection

A

usually in 1-3 months
symptoms non-specific until late in the rejection process
dysrythmias
hypotension, weakness, fatigue, dizziness
endomyocardial biopsies at regular specified times

17
Q

treatment of a transplant rejection

A

high dose IV steriods

antilymphocyte globulin and T cell monoclonal antibody

18
Q

why can transplant rejection be hard to detect?

A

it can mimic se of immunosuppresent drugs

19
Q

chronic rejection

A

occur in months to years

progressive loss of function, return of original s/s, renal- dialysis, pancreas-insulin, liver- new graft