Toxins and Antidotes Flashcards by Mary Potkonjak

Q

Acetaminophen

A

N-acetylcysteine - replenishes glutathione

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Q

AChE inhibitors/organophosphates

A

Atropine + pralidoxime

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Q

Amphetamines (basic)

A

NH4Cl - acidify urine

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Q

Antimuscarinic/anti-cholinergic agents

A

Benzos
Physostigmine confirms the diagnosis
Sodium bicarbonate to narrow QRS

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Q

β-blockers

A

Glucagon

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Q

Carbon monoxide

A

100% O2

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Q

Copper, arsenic, gold

A

Penicillamine

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Q

Cyanide

A

Nitrate + Thiosulfate, hydroxocobalamin

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Q

Digitalis

A

Anti-dig Fab fragments

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Q

Heparin

A

Protamine sulfate

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Q

Iron

A

Deferoxamine, deferasirox

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Q

Lead

A

EDTA, dimercaprol, succimer, penicillamine

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Q

Mercury, arsenic, gold

A

Dimercaprol (BAL), succimer

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Q

Methanol, ethylene glycol

A

Fomepizole > ethanol, dialysis

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Q

Methemoglobin

A

Methylene blue, vitamin C

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Q

Opioids

A

Naloxone

Q

Salicylates

A

NaHCO3 (alkalinize urine), dialysis

Q

TCAs

A

NaHCO3 (plasma alkalization)

Q

tPA, streptokinase, urokinase

A

Aminocaproic acid

Q

Warfarin

A

Vitamin K, FFP (if bleeding)