Topic 6: Aldehyde/Ketone Reactions Flashcards
1
Q
Carbonyl with NaCN, HCN, KCN (basic conditions)
A
creation of a cyanohydrin (OH and CN on the same carbon), keep carbon skeleton
2
Q
Carbonyl with a ylide
A
Connect the carbons of the ylide and carbonyl compound, with a double bond in between (similar to ozonolysis)
3
Q
Does the Wittig reaction have an intermediate?
A
Yes, a 4 member ring with the Phosphorus and Oxygen
4
Q
What is the major conformation of the Wittig Reaction?
A
(Z) cis-alkene
5
Q
Cyanide Nu- additions work best in _____ conditions
A
basic
6
Q
The lower the pKa, the more ____ and the least _____
A
acidic; nucleophilic
7
Q
______ is the weakest carbon nucleophile studied
A
Cyanide
8
Q
T/F: Cyanohydrin formation is reversible
A
true
9
Q
The addition of carbon nucleophiles to aldehydes and ketones is under _______ conditions
A
basic.
