TOPIC 4 - DNA GENES CHROMOSOMES Flashcards

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1
Q

describe the structure of DNA?

A

-deoxyribose sugar
-phosphate group
-organic base ( ATCG)
-double stranded
-H bonds between bases which form helix shape

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2
Q

what are three components of nucleotides?

A

phosphate group , sugar , base

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3
Q

describe the role of DNA?

A

carries genetic information, determines our inherited characteristics

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4
Q

describe the structure of RNA?

A
  • ribose sugar
    -phosphate group
    -organic base (AUCG)
    -single stranded
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5
Q

describe the role of RNA?

A

transfers information from DNA to ribosomes during protein synthesis

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6
Q

which bases are purine and pyrimidine?

A

purine - double ring - AG
pyrimidine - single ring - TCU

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7
Q

how is DNA in eukaryotic cells different from in prokaryotic cells?

A

Eukaryotic cells -
- found in nucleus
- long and linear
- bound by histone proteins to form chromosomes
- mitochondria and chloroplast contain prokaryotic -like DNA

Prokaryotic cells-
- short circular
- not associated with proteins

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8
Q

what is the genetic code?

A

the order of bases on DNA. Consists of codons - triplets of bases which codes for a particular amino acid

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9
Q

what is a gene?

A

A sequence of bases on a DNA molecule that codes for a specific sequence of amino acids to make a polypeptide. Can also code for functional RNA

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10
Q

what is a locus?

A

the location of a particular gene on a chromosome

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11
Q

what is an allele?

A

different forms of the same gene found at the same locus of a chromosome

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12
Q

what are exons and introns?

A

EXONS = regions of DNA that code for amino acid sequences, separated by one or more introns

INTRONS = regions of DNA that do not code for amino acids. Found in eukaryotic DNA not prokaryotic. It is spliced (removed) our of mRNA molecules.

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13
Q

where are introns

A

between exons
within genes

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14
Q

identify features of the genetic code?

A

Non overlapping
Degenerate
Universal

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15
Q

what does DEGENERATE mean?

A

more than one triplet base codes for 1 Amino Acid.
64 possible triplets for 20 amino acids

Advantage - if point mutation occurs, it may still code for the same Amino Acid and therefore have no effect

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16
Q

what does UNIVERSAL mean?

A

same triplet of bases codes for the same amino acids in ALL organisms

Advantage - genetic engineering is possible
eg inserting gene for human insulin into bacteria

17
Q

what does NON OVERLAPPING mean?

A

each triplet is only read once
eg ACG - GCT - TCA

Advantage - if there is a point mutation it will only affect one codon and therefore one amino acid.