Tissu Osseux Flashcards

1
Q

De quel type de collagene est composé le TO

A

Tissu conjonctif de soutient composé d’une MEC riche en collagène de type 1 minéralisé

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2
Q

Quels sont les 4 grands rôles du TO

A

Mécanique / réserve de Ca2+/ Hématopoïèse/ endocrinienne

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3
Q

Vf les os os long ont une ossification membranaire

A

Faux

Os long= ossification enchondrale a partir d’une ébauche cartilagineuse

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4
Q

Quel type d’ossification ont les os courts

A

Membranaire

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5
Q

Comment appelle t’on le TO primaire

A

Tissé

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6
Q

Vf: le TO secondaire est lamellaire

A

Vrai

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7
Q

Proportion os cortical / trabeculaire

A

Cort 80% et trab 20%

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8
Q

Ou retrouve t’on de l’os compact cortical et de l’os spongieux

A

Compact = diaphyse des os long
+Enveloppe os court plat
Spongieux: Epiphyse et metaphyse
+ os plat court

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9
Q

Structure breve os compact

A

Juxtaposition d’osteon cylindrique centré sur le canal de Harvers relié entre par canaux de volkman

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10
Q

Structure os spongieux

A

En traves orientes en reponse aux contraintes mécaniques

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11
Q

Role de los commpact + spongieux

A
Cortical = resistance mécanique +++
Spongieux = echange metabolique
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12
Q

Quelle hormone reactive les cell bordantes en ob actif

A

Pathormone

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13
Q

Organisation collagene os lamellaire os tissé

A

Lamellaire v juxtaposition de lamelle parallèle biréfringente
Tissé: synthese de collagene de façon désorganisée en mosaique

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14
Q

Qu’est-ce que l’osteocalcine

A

Vit K dépendant
Spe du to
Dosage sanguinn possible

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15
Q

A quoi servent les siblings

3 exemples + localisation

A

Role minéralisation
Osteopontine= os rein
Sialoproteine = os
DMPI= osteocyte

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16
Q

A quelle famille appartiennent la decorine et biglycan

+ quel rôle

A

Proteoglycanes servant a l’agencement des molecules de collagene dans la matrice

17
Q

Poids du calcium dans squelette

A

1kg ( 1100g 1200g)

18
Q

Duree remodelage osseux

A

4 mois chez l’adulte

19
Q

Quelle molecule inhibe rank L

A

Osteoprotegerine