TIDM + TIIDM Flashcards

1
Q

in what circumstances does NICE recommend starting a patient on a continuous insulin infusion in patients with TIDM?

A
  • Persistent hyper/hypoglycaemia despite being on multiple daily injections
  • If the patient is < 12 years of age and multiple insulin injections are inappropriate or impractical
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2
Q

what type of condition is TIDM?

A
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3
Q

what type of condition is TIIDM?

A
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4
Q

in which type of diabetes do beta cells become damaged?

A

both

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5
Q

what’s the classic triad of symptoms of TIDM in children?

A
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6
Q

Give an example of a long-acting insulin given for management of TIDM?

A
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7
Q

Give an example of a short-acting insulin given for management of TIDM?

A
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8
Q

summary of management of TIDM?

A
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9
Q

what three things need to be monitored by the patient in TIDM?

A
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10
Q

what are the four criteria that are used to diagnose TIIDM?

A
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11
Q

what happens in an OGTT?

A
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12
Q

what’s normal range for blood glucose?

A
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13
Q

what percentage of diagnosed diabetes is TIIDM?

A
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14
Q

which study proved that TIIDM is reversible?

A
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15
Q

what’s 1st, 2nd and 3rd line medical management for TIIDM?

A
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16
Q

what are the two main effects of metformin?

A
17
Q

what are the three main side effects of metformin?

A
18
Q

what four drugs can be given in addition to metformin in second line TIIDM treatment?

A
19
Q

what’s third line treatment for TIIDM?

A
20
Q

what’s first line treatment for TIIDM?

A
21
Q

does the body metabolise metformin? how is it cleared?

A
  • Metformin is not metabolized.
  • It is cleared from the body by tubular secretion and excreted unchanged in the urine
22
Q

what’s the average elimination half life of metformin?

A
  • 6.2 hours
    (it is undetectable in blood plasma within 24 hours of a single oral dose)
23
Q

where does metformin accumulate?

A
  • RBCs
    (has a longer elimination half life of 17.6 hours)