THYROID GLAND

Question 1

Largest endocrine gland?

Answer 1

Thyroid gland

Question 2

Hormones by thyroid gland:

Answer 2

Thyroxine , Triodothyronine, calcitonin.

Question 3

Thyroid hormones are controlled by which pituitary hormone?

Answer 3

Thyroid stimulating hormone.

Question 4

Which cells of thyroid gland forms calcitonin?

Answer 4

C cells

Question 5

Quantity of iodine required for formation of thyroid hormones?

Answer 5

1 mg/week

Question 6

Iodine is taken in the diet in the form of

Answer 6

Iodide

Question 7

Transporters used for iodide transport in thyroid gland

Answer 7

Sodium iodide cotransporter

Chloride iodide counter transporter(pendrin)

Question 8

Enzyme for iodide oxidation in thyroid gland

Answer 8

Peroxidase

Question 9

Attachment of oxidised iodide to thyroglobulin is called?

Answer 9

ORGANIFICATION OF THYROGLOBULIN

Question 10

Percentage of Thyroid hormones formed are?

Answer 10

T3 - 93%

T4 - 7%

Question 11

Plasma proteins used for hormones (Thyroid) transport?

Answer 11

TBG

TBPA

Question 12

Which has more binding affinity to PPs , T3/T4

Answer 12

T4

Question 13

Thyroglobulin is stored in ?

Answer 13

Thyroid follicles

Question 14

Deiodinases responsible for conversion of T4 to T3

Answer 14

D1,D2

Question 15

Deiodinase responsible for excretion of T3,T4 by adding sulphates or glucoronidation

Answer 15

D3

Question 16

Which aspect of body decreases with increase in TH activity

Answer 16

Body weight

Question 17

What are stimulatory effects of TH on CVS

Answer 17

Increased CO
Increased blood flow
Increased heart strength

Question 18

Stimulatory effects of TH on Respiratory system.

Answer 18

Increased rate and depth of respiration

Question 19

Stimulatory effects of TH on CNS

Answer 19

Increased activity of synapses

Increased rate of cerebration

Question 20

Stimulatory effects of TH on GIT

Answer 20

Increased motility of cells

Question 21

Effect of TH on BMR

Answer 21

Increases

Question 22

Effect of TH on male sexual functions

Answer 22

Increased TH causes impotence

Decreased TH causes loss of libido

Question 23

Effect of TH on female sexual functions

Answer 23

Increased TH causes oligomenorhoea

Decreased TH causes polymenorhoea and loss of libido

Question 24

Effect of TH on carbohydrate metabolism

Answer 24

Increases every aspect of it.

Question 25

Effect of TH on fat metabolism

Answer 25

Increases lipolysis and decreases cholesterol and TGs from plasma

Question 26

Effect of TH on protein metabolism

Answer 26

Increases both synthesis and degradation while

Hyper physiological states causes more of degradation.

Question 27

Hormones regulating TH

Answer 27

TSH , TRH

Question 28

Functions of TSH to increase thyroid functions

Answer 28

Increased iodine uptake and increased ORGANIFICATION and increased oxidation of I-

Question 29

Drugs for inhibition of thyroid activities

Answer 29

:Thiocynate
:Propylthiouracyl
:High conc.of I-

Question 30

Hyperthyroidism includes:

Answer 30

Graves disease
Adenoma
Exopthalmos

Question 31

Antibodies formed in Graves disease

Answer 31

Thyroid stimulating immunoglobulins

Question 32

Autoimmune disorder for hyperthyroidism

Answer 32

Hashimoto disease causing thyroiditis

Question 33

Hyperthyroidism in adults

Answer 33

Myxedema

Question 34

Hyperthyroidism in fetal life

Answer 34

Cretinism

Question 35

Artherosclerosis develops in hyper or hypo thyroidism

Answer 35

Hypothyroidism due to increased cholesterol levels in plasma