thyroid disorders

Question 1

signs of hyperthyroidism

Answer 1

hyperactive/lethargic, CVS changes, weight loss w variable appetite, thyroid nodule

Question 2

CVS changes in hyperthyroidism

Answer 2

tendency for tachycardia and dysrhythmias, gallop rhythms, decreased vasc resistance = increased cardiac inotropy and chronotropy = damage and HF

Question 3

Clin path in hyperthryoidism

Answer 3

stress leukogram, elevated ALT, physiological neutrophilia, azotaemia, elevated ALP, elevated bile acids

Question 4

best way to dx of hyperthryoidism

Answer 4

basal tT4 = high specificity

Question 5

follow up testing for hyperthyroidism

Answer 5

T3 suppression test, thyroid scintigraphy, repeat basal tT4

Question 6

mx tx for hyperthyroidism

Answer 6

methimazole/carbimazole but with bad side effects = depression, lethargy, GI signs

Question 7

other tx for hyperthyroidism

Answer 7

unilateral/bilateral thyroidectomy, thyroid irradiation, diet alterations

Question 8

signs of hypothyroidism

Answer 8

dermal changes, exercise intolerance, overweight, lethargy, neuro problems occassionally

Question 9

chin path of hypothyroidism

Answer 9

non-specific = elevated serum cholesterol, serum CK, proteinuria? mild non-regent anaemia?

Question 10

dx for hypothyroidism

Answer 10

basal free t4, basal TSH, basal tT4, TSH response test, thyroglobulin ABs?

Question 11

tx for hypothyroidism

Answer 11

thyroxine tablets given orally