Thrombolytic Management

Question 1

What two thrombolytics are available for acute stroke treatment?

Answer 1

alteplase and tenecteplase

Question 2

Which thrombolytic is FDA approved for acute stroke treatment?

Answer 2

alteplase

Question 3

What is the blood pressure parameter needed to administer a thrombolytic?

Answer 3

<185/110 mmHg

Question 4

What is the blood pressure parameter after a thrombolytic is administered?

Answer 4

<180/105 mmHg

Question 5

What two complications are possible after a thrombolytic is administered?

Answer 5

Hemorrhage and Angioedema

Question 6

What medications are held for 24 hours after a thrombolytic is administered?

Answer 6

Antiplatelets and Anticoagulants

Question 7

What is needed to calculate a thrombolytic dose?

Answer 7

Accurate patient weight

Question 8

What is the dose of alteplase to treat acute ischemic stroke?

Answer 8

0.9mg/kg/hr, max dose of 90mg

Question 9

What is the dose of tenecteplase to treat acute ischemic stroke?

Answer 9

.25mg/kg IV push, max dose of 50mg

Question 10

What is the next step when alteplase has finished infusing?

Answer 10

Run a 50cc bag of Normal Saline at the same administration rate as the alteplase