Things Flashcards

1
Q

US findings diagnostic of pregnancy failure

A
  1. CRL 7mm, or more, and no heartbeat
  2. Mean sac diameter of 25mm, or more, and no embryo
  3. No embryo with a heartbeat 14 days or more after a scan that showed a gestational sac without a yolk sac
  4. No embryo with a heartbeat 11 days after a scan that showed a gestational sac with a yolk sac
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2
Q

US findings suspicious for, but not diagnostic of, pregnancy failure

A
  1. CRL less than 7mm and no heartbeat
  2. Mean sac diameter of 16-24mm and no embryo
  3. No embryo with a heartbeat 7-13 days after a scan that showed a gestational sac without a yolk sac
  4. No embryo with a heartbeat 7-10 days after a scan that showed a gestational sac with a yolk sac
  5. Empty amnion (amnion seen adjacent to yolk sac, with no visible embryo)
  6. Enlarged yolk sac (greater than 7mm)
  7. Small gestational sac in relation to the size of the embryo (less than 5mm difference between mean sac diameter and CRL)
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3
Q

What criteria is used to be able to consider medical management of early pregnancy loss?

A
Women without
- infection 
- hemorrhage
- severe anemia 
- bleeding disorders
Women who want to shorten time to complete expulsion but want to avoid surgery
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4
Q

Stillbirth risk factors

A
Non-Hispanic black race
Nulliparity (increased rate at extremes of parity- >3 prior pregnancies)
Advanced maternal age
Obesity
Pre-existing diabetes
Chronic hypertension
Smoking
Alcohol use
Use of ART (assisted reproductive technology)
Multiple gestations
Male fetal sex
Unmarried status
Past OB history 
- hx stillbirth 
- hx preterm delivery
- hx FGR (highest risk with Hx FGR delivered <32wk)
- hx Pre-E
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5
Q

How do you describe Fetal Kick Counts?

A

One method is to write down how long it takes the fetus to make 10 movements each day.
To do this choose a time when the fetus is usually active. (After eating)
Each baby has its own level of activity and most have a sleep cycle of 20-40 min.
Alert your doctor if there is a change from the normal pattern or number of movements.
- ACOG patient eduction pamphlet

10 movement in 2 hours
Start @ 28wk?
Lack of evidence to support fetal kick counts

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6
Q

Type of Antepartum Tests for fetal well being

A
Fetal kick count
NST (Vibroaccoustic stimulation) 
Oxytocin challenge test or Contraction stress test
Biophysical Profile
Modified BPP
Doppler studies
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7
Q

Causes of baseline abnormalities:

Bradycardia

A
Fetal distress
Cord compression 
Heart block
Maternal hypothermia
Maternal drug
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8
Q

Causes of baseline abnormalities:

Tachycardia

A
Maternal Pyrexia
Thyrotoxicosis 
Maternal acidosis &/or ketosis
Hypoxia
Fetal cardiac anomaly (SVT)
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9
Q

Describe FHR variability

A

Determined over a 10 min period

Fluctuations in baseline of IRREGULAR amplitude and frequency

(Regular would be sinusoidal)

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10
Q

Causes of decreased FHR variability

A
Fetal sleep state
Hypoxia or fetal metabolic acidosis (pH <7 & base deficit =/> 12 mmol/L)
Prematurity 
Neurologic problem 
Certain fetal anomalies
Medications
- Mag sulfate
- General anesthesia
- Narcotic
- Barbiturates
- Tranquilizers
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11
Q

Causes of Sinusoidal FHRs

A
Fetal anemia (any etiology)
- Rh isoimmunization
- Parvo virus infection w/ anemia
- Anemia due to fetomaternal hemorrhage
Medications 
- Narcotics
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12
Q

Fetal Arrhythmias

A

Audible arrhythmias: interment or skipped beats.
- 95% will spontaneously resolve if there are no cardiac anomalies
Most common: Atrial PAC –> SVT (220-240bpm) followed by atrial fibrillation or flutter
- Fetal arrhythmia >200bpm
- Complete heart block 50-70bpm
- SLE or Sjorgens syndrome with antibodies (Anti-Ro or Anti-La)

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13
Q

FHT reactivity based on gestational age

A

24-28wk: 50% (28 75%)
28-32: 85%
34wk: 95%

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14
Q

Early Deceleration

A

Nadir at the same time as peak of contraction

May signify head compression - increase parasympathetic output from fetal brain to fetal SA node

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15
Q

Late Decelerations

A

Nadir after the peak of contraction

May signify utero-placenta insufficiency

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16
Q

What is an adequate Contraction Stress Test

A

Need at least 3 contractions, of moderate intensity, in 10 min, lasting 40-60 seconds

Need to observe pt until uterine activity return to baseline

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17
Q

Contraction Stress Test Interpretation

A
  • Negative: No late or significant variable decels
  • Positive: late decels after >50% of contractions (even if contraction frequency is < 3 in 10 min)
  • Equivocal-Suspicious: intermittent late )<50%) decels or significant variable decels
  • Equivocal: decels with contractions that are more frequent than every 2 min or lasting longer than 90 seconds
  • Unsatisfactory: less than 3 contractions in 10 min or an uninterpretable tracing
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18
Q

Contraindications to CST

A

PB: any condition that is contraindicated to labor or vaginal delivery

ABC Video: 
PPROM/PROM
Previa
Multiple gestation
Preterm labor
Hx classical CS or uterine surgery involving myometrium
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19
Q

Components of BPP

A
  • NST reactive
  • Fetal movement: 3 discrete body or limb movements in 30 min
  • Fetal tone: 1 extension/flexion of extremity, opening/closing hand
  • Fetal breathing: 30 sec in 30 min
  • Normal amniotic fluid volume: vertical pocket =/>2
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20
Q

Ultrasound findings consistent with placenta accreeta specrum

A
  • Placental lacunae at 15-20 weeks
  • Thinning of myometrium at placental site
  • loss of retroplacental clear space
  • Increased vascularity of the uterine serosa-bladder interface
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21
Q

Hypothesis of the etiology of placenta accreta spectrum

A

A defect in the endometrial-myometrial interface leads to failure of normal decidualization in the area of the uterine scar, which allows for abnormally deep placental anchoring villi and trophoblast infiltration

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22
Q

Definition of placenta accreta

A

abnormal trophoblast invasion into the uterine myometrium

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23
Q

Decidualization

A

Transformation of endometrial stromal fibroblasts into specialized secretory decidual cells that provide a nutritive and immunoprivileged matrix essential for embryo implantation and placental development.

24
Q

Risks factors for placenta accreeta

A
History of cesarean delivery 
Placenta previa 
AMA
Multiparity
Prior uterine surgery or curettage
Asherman syndrome
25
Q

Contraindications to HRT use

A
  • Pregnancy
  • Hx or current breast cancer
  • Estrogen sensitive tumor
  • Undiagnosed vaginal bleeding
  • Severe liver disease
  • Hx of DVT
26
Q

How to you determine who needs osteoporosis screening

A
  • I perform a risk assessment of my patients
  • Standard screening at age 65
  • Using a FRAX score I determine if a pt with risk factors needs earlier screening
27
Q

Who needs early osteoporosis screening?

A

Screen with DXA if < 65 &

- FRAX >/= 9.3%

28
Q

When should pharmacologic treatment of osteoporosis start?

A

Pt has osteoporosis ( T score 3%

FRAX Major osteoporotic fracture risk >20%

29
Q

Diagnosis Osteoporosis

- What other tests needs to be ordered after the diagnosis of osteoporosis is made

A
  • CBC
  • Metabolic panel: phosphate & renal function (looks at calcium excretion)
  • TSH, Free T4
  • Vit D (25-OH vit D assay)
  • 24 hr urine Ca/PTH

Endocrinology will order

  • Celiac panel
  • Protein electrophoresis
30
Q

DDx maculopapular rash on palms & soles

A

Secondary syphilis
Hand foot mouth Dz (coxsackie virus)
Rocky Mountain spotted fever

31
Q

Dysgerminoma tumor markers

A

B-hCG

LDH

32
Q

Endodermal sinus tumor markers

A

AFP

33
Q

Choriocarcinoma tumor markers

A

B-hCG

34
Q

Immature treating tumor markers

A

AFP
LDH
CA-125

35
Q

Embryonal carcinoma tumor markers

A

B-hCG

AFP

36
Q

Ovarian germ cell tumors

A
Dysgerminoma
Endodermal sinus 
Choriocarcinoma
Immature terrains
Embryonal carcinoma
37
Q

Ultrasound findings concerning for ovarian malignancy

A
Greater than 10 cm
Septations 
Papillary or solid components
Irregularities
Presence of ascites
High color Doppler flow
38
Q

Ultrasound findings of benign ovarian masses

A

Thin, smooth walls

Absence of solid components, septations, or internal blood flow on color Doppler ultrasound

39
Q

No malignant causes of elevated CA-125

A
Pregnancy
Endometriosis 
Uterine leiomyomas
PID
Inflammatory conditions - Inflammatory Bowel Disease (UC/Crohns),SLE
40
Q

IV pyelogram

Pyelography

A

Evaluate patency of ureters

-looks for obstruction

41
Q

Voiding cystogram

A

Evaluate bladder for defects (including checking the integrity of a cystotomy repair)

A fluoroscopic study of the bladder performed while the patient is voiding. If a cystotomy repair or urethral anastomoses continues to leak, contrast will be visualized escaping the cavity

42
Q

Sensitivity

A

Ability to correctly diagnose the disease

Given the pt has the disease, what are the chances the test will be positive

TP/(TP+FN)

43
Q

Specificity

A

Ability to correctly exclude the disease

Given the pt does not have the disease, what are the chances the test will be negative

44
Q

Positive predictive value

A

Chances that a positive results is correct

Given the test if positive, what are the chances the patient has the disease

TP/(TP+FP)

45
Q

Negative predictive value

A

Chances that a negative result is correct

Given the test is negative, what are the chances the patient does not have the disease

TN/(TN+FN)

46
Q

Incidence

A

New cases over a given period of time

47
Q

Prevalence

A

Total cases at a specific point in time

48
Q

Areola dermatome

A

T4

49
Q

Xihisternum dermatome

A

T8

50
Q

Umbilicus dermatome

A

T10

51
Q

Pubis dermatome

A

T12

52
Q

Perineum dermatome

A

S2-4

53
Q

Pudendal nerve

A

S2,3,4
Innervated the perineum

(Second stage of labor pain)

54
Q

Erb’s palsy

A

C5-C6 of brachial plexus
medial rotation of arm
Grasp reflex intact

55
Q

Klumpke’s palsy

A

C8-T1 of brachial plexus
hand and wrist paralysis, arm hangs at side
No grasp reflex