the kidney - nephron Flashcards
Bowman’s capsule
where ultrafiltration occurs
Ultrafiltration
- blood enters glomerulus from the aorta (high pressure)
- the pressure forces fluid into Bowman’s capsule - glomerular filtrate
- filters - allowing small molecules through (e.g. glucose) but not large molecules (e.g. proteins)
Selective reabsorption - which molecules are reabsorbed?
glucose - needed for respiration to release energy
amino acids - needed to build proteins
urea
sodium ions
chloride ions
water
PCT
MOST REABSORPTION BACK INTO BLOOD HAPPENS HERE:
generally all of the reabsorbed molecules are actively transported into the blood (which requires energy)
Loop of Henle
USED TO CONCENTRATE THE URINE
DESCENDING LIMB:
- water is reabsorbed via osmosis
ASCENDING LIMB:
- impermeable to water
- Na and Cl ions transported out of here to create LWP in the fluid so water moves out via osmosis in the descending limb
DCT
USED TO ‘MOP UP’ ANY REMAINING REABSORPTION
- more Na and Cl ions reabsorbed
- more water reabsorbed
- ammonium ions are secreted into the filtrate
Collecting duct
SELECTIVE REABSORPTION OF WATER
What controls the permiability of Collecting duct?
ADH
What does it mean if ADH IS PRESENT in the collecting duct?
open channels in collecting duct - allows more water to be reabsorbed - urine concentration increases, volume of urine decreases
What does it mean if ADH IS NOT PRESENT in the collecting duct
Channels shut - water not reabsorbed - urine concentration decreases, volume of urine increases