the kidney - nephron Flashcards

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1
Q

Bowman’s capsule

A

where ultrafiltration occurs

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2
Q

Ultrafiltration

A
  • blood enters glomerulus from the aorta (high pressure)
  • the pressure forces fluid into Bowman’s capsule - glomerular filtrate
  • filters - allowing small molecules through (e.g. glucose) but not large molecules (e.g. proteins)
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3
Q

Selective reabsorption - which molecules are reabsorbed?

A

glucose - needed for respiration to release energy
amino acids - needed to build proteins
urea
sodium ions
chloride ions
water

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4
Q

PCT

A

MOST REABSORPTION BACK INTO BLOOD HAPPENS HERE:
generally all of the reabsorbed molecules are actively transported into the blood (which requires energy)

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5
Q

Loop of Henle

A

USED TO CONCENTRATE THE URINE

DESCENDING LIMB:
- water is reabsorbed via osmosis

ASCENDING LIMB:
- impermeable to water
- Na and Cl ions transported out of here to create LWP in the fluid so water moves out via osmosis in the descending limb

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6
Q

DCT

A

USED TO ‘MOP UP’ ANY REMAINING REABSORPTION
- more Na and Cl ions reabsorbed
- more water reabsorbed
- ammonium ions are secreted into the filtrate

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7
Q

Collecting duct

A

SELECTIVE REABSORPTION OF WATER

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8
Q

What controls the permiability of Collecting duct?

A

ADH

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9
Q

What does it mean if ADH IS PRESENT in the collecting duct?

A

open channels in collecting duct - allows more water to be reabsorbed - urine concentration increases, volume of urine decreases

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10
Q

What does it mean if ADH IS NOT PRESENT in the collecting duct

A

Channels shut - water not reabsorbed - urine concentration decreases, volume of urine increases

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